Browse our Review Articles

This quick reference guide for researchers addresses common misconceptions in the use of covariates in observational research and offers tips for preventing misstatements and mistakes.

Classification of MET mutations allows a better understanding of sensitivity and resistance to targeted therapies used in cancer.

A comprehensive review focusing on the role of osteoclasts as active regulators of bone homeostasis by influencing osteoblast function explores the currently known mechanisms and coupling factors involved in osteoclast–osteoblast communication and their potential as treatments for bone diseases.

An integrative conceptual and mathematical framework of immune variation that includes unique basal profiles associated with differential susceptibility to disease, distinct acute immune signatures associated with disease severity, and how different determinants can lead to individual pathways of illness outcome.

Recent advances in Bayesian optimal experimental design have made it possible to improve the efficiency and informativeness of experiments using machine learning, and shed new light on considerations that affect machine learning assisted experimental designs and computational models in general.

This article reviews the latest studies that have used super-resolution microscopy and cluster analysis methodologies to study the mechanism of protein kinase signalling hubs and their organisation at nanoscale.

A synthetic, prospective article considers how the fields of sensory ecology and collective behaviour can combine when considering animal collective movements and interactions, and how these fields can inspire each other to advance understanding of animal behaviour, adaptation and evolution.

Circular analyses of knowledge are a common, serious, but often manageable problem in systems and network neuroscience.

Researchers and administrators can integrate reproducible research and open science practices into daily practice at their research institutions by adapting research assessment criteria and program requirements, offering training, and building communities.

A critical re-evaluation of some of the quintessential examples given as evidence for cortical reorganisation argues that, contrary to the prevalent view, any opportunities for functional change in cortical organisation are incremental and constrained by the underlying structural ‘blueprint'.