Browse our Review Articles

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    1. Computational and Systems Biology
    2. Ecology

    Data-driven causal analysis of observational biological time series

    Alex Eric Yuan, Wenying Shou
    Visualizations, simulations, and examples are used to provide an accessible synthesis of the reasoning and assumptions behind commonly used causal discovery approaches.
    1. Neuroscience

    Understanding implicit sensorimotor adaptation as a process of proprioceptive re-alignment

    Jonathan S Tsay, Hyosub Kim ... Richard B Ivry
    A new computational model reveals how implicit sensorimotor adaptation is elicited to re-align one's felt and desired hand position.
    1. Cell Biology
    2. Chromosomes and Gene Expression

    Hematopoietic plasticity mapped in Drosophila and other insects

    Dan Hultmark, István Andó
    A critical analysis of recent single-cell transcriptomic studies of Drosophila blood cells confirms the extreme plasticity of the major phagocyte class, identifies a new class of blood cell, and suggests relationships to blood cells in other insects.
    1. Medicine

    Evolution of multiple omics approaches to define pathophysiology of pediatric acute respiratory distress syndrome

    Jane E Whitney, In-Hee Lee ... Sek Won Kong
    Multiple -omics approaches have provided valuable insight into the pathobiology of pediatric acute respiratory distress syndrome, and novel unbiased techniques hold promise for future discoveries.
    1. Medicine

    Microscopic colitis: Etiopathology, diagnosis, and rational management

    Ole Haagen Nielsen, Fernando Fernandez-Banares ... Darrell S Pardi
    State-of-the-art knowledge of microscopic colitis, a disease often more prevalent than ulcerative colitis and Crohn’s disease among elderly people, is provided from a global perspective with the overall aim to create better awareness and improve rational management.
    1. Evolutionary Biology

    Fitness consequences of outgroup conflict

    Ines Braga Goncalves, Amy Morris-Drake ... Andrew N Radford
    A detailed discussion of the broad range of immediate, delayed, cumulative, and third-party fitness consequences arising from outgroup conflict showcases the importance of this neglected aspect of sociality as a powerful and widespread evolutionary force.
    1. Neuroscience

    Human muscle spindles are wired to function as controllable signal-processing devices

    Michael Dimitriou
    By acting as versatile signal-processors that encode flexible coordinate representations, muscle spindles challenge current widely held views concerning the role of proprioceptors and the peripheral nervous system in sensorimotor function.
    1. Microbiology and Infectious Disease

    Metabolic arsenal of giant viruses: Host hijack or self-use?

    Djamal Brahim Belhaouari, Gabriel Augusto Pires De Souza ... Sarah Aherfi
    Metabolic pathways found to date in giant virus raise the question if these viral enzymes provide some level of autonomy to viruses or if they are used to expand the host metabolism.
    1. Neuroscience

    Neural mechanisms underlying the temporal organization of naturalistic animal behavior

    Luca Mazzucato
    Naturalistic animal behavior exhibits a complex organization in the temporal domain, whose variability stems from hierarchical, contextual, and stochastic sources and can be naturally explained in terms of metastable attractor models.
    1. Computational and Systems Biology
    2. Neuroscience

    Combining hypothesis- and data-driven neuroscience modeling in FAIR workflows

    Olivia Eriksson, Upinder Singh Bhalla ... Jeanette Hellgren Kotaleski
    Increased usability and validity of neuroscience models, through FAIR workflows for the whole modeling process, including data and model management, parameter estimation, uncertainty quantification, and model analysis.