Browse our Review Articles

Page 17 of 18
    1. Neuroscience

    Hyperalignment: Modeling shared information encoded in idiosyncratic cortical topographies

    James V Haxby, J Swaroop Guntupalli ... Ma Feilong
    Hyperalignment provides a conceptual framework for cortical architecture that captures how shared information is encoded in idiosyncratic cortical topographies that preserve vector geometry for population response and connectivity patterns.
    1. Neuroscience

    Mechanisms of competitive selection: A canonical neural circuit framework

    Shreesh P Mysore, Ninad B Kothari
    A first principles, neuro-computational framework proposes a path for the experimental dissection of neural circuit mechanisms of competitive selection across brain areas and animal species.
    1. Cancer Biology
    2. Immunology and Inflammation

    The tumor microenvironment as a metabolic barrier to effector T cells and immunotherapy

    Aaron R Lim, W Kimryn Rathmell, Jeffrey C Rathmell
    Diverse components of the tumor microenvironment affect T cell metabolism in ways that are crucial to improving immunotherapy.
    1. Ecology
    2. Neuroscience

    The social life of Norway rats (Rattus norvegicus)

    Manon K Schweinfurth
    Rats are highly social animals that show complex social skills, which has not been acknowledged enough when controlling them in the wild and conducting research in the laboratory.
    1. Neuroscience

    Prediction signals in the cerebellum: Beyond supervised motor learning

    Court Hull
    Emerging evidence suggests a broad role for cerebellar circuits in generating and testing predictions about movement, reward, and diverse cognitive processes.
    1. Plant Biology

    A roadmap for gene functional characterisation in crops with large genomes: Lessons from polyploid wheat

    Nikolai M Adamski, Philippa Borrill ... Cristobal Uauy
    The development of genomic tools and publicly available resources in polyploid wheat provides a framework to understand biologically important traits in crops with large genomes.
    1. Epidemiology and Global Health

    The hazards of smoking and the benefits of cessation: A critical summation of the epidemiological evidence in high-income countries

    Prabhat Jha
    Cumulatively, from 1950 to 2015, smoking-related disease has been the biggest cause of premature death in high-income countries, with elevated risks of smoking continuing well into the 21st century.
    1. Cancer Biology

    Understanding the glioblastoma immune microenvironment as basis for the development of new immunotherapeutic strategies

    Ana Rita Pombo Antunes, Isabelle Scheyltjens ... Jo A Van Ginderachter
    The heterogeneity of immune cell types in glioblastoma tumors depends on the tumor's genetic make-up and treatment status and is an incompletely mined source of novel therapeutic targets.
    1. Cancer Biology
    2. Immunology and Inflammation

    Preclinical murine tumor models: A structural and functional perspective

    Marion V Guerin, Veronica Finisguerra ... Alain Trautmann
    Dissecting structural, cellular and molecular differences between transplanted and spontaneous mouse tumor models, highlighting their relevance for predicting the efficacy of anti-cancer treatments in patients.
    1. Developmental Biology
    2. Evolutionary Biology

    Resolving homology in the face of shifting germ layer origins: Lessons from a major skull vault boundary

    Camilla S Teng, Lionel Cavin ... J Gage Crump
    Homology of vertebrate skull structures should be based on evolutionary continuity and an appreciation of germ layer origins and inductive signaling in the embryonic head.