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The mammalian Y chromosome has become specialised for male fertility, but exact functions of individual Y genes remain poorly understood, a knowledge gap that new approaches can bridge.

Latest advances in biological timing studies substantiate an emerging concept of autonomous clocks that are normally entrained by the cell cycle and/or the circadian clock to run in synchrony, but have evolved to run independently to regulate different cellular events.

An integrated empirical paradigm tracing immune strategies, underlying mechanisms and infection outcomes across reservoir host-pathogen systems, their specific ecological contexts, life-history features, and coevolutionary dynamics can reveal the actual patterns and processes underlying spillover in the wild.

The shared capacity of stem cells to recapitulate initial body plan formation in vitro without species-specific cues, suggests the existence of alternative, evolutionarily conserved developmental trajectories.

A computationally explicit framework can explain post-decisional neural signals of performance monitoring.

Mosquitoes may be likely to adapt to climate warming given their short life cycles and strong temperature sensitivity, but key data gaps identified here constrain current estimates of adaptive potential.

With standardized insecticide-resistance assays failing to inform mosquito-control efficacy due to genotype-by-environment effects, practical resistance monitoring under relevant local conditions is needed to correlate resistance, mosquito-control efficacy, and disease epidemiology.

A synthesis of recent hybridization literature reveals emerging patterns in the evolution of genomes after hybridization, processes proposed to explain those patterns, and important open questions to direct future hybrid genomics research.

Micron-scale geometrical features of individual microtubule polymers and polymer networks encode information that guides the self-organization of microtubules into specialized structures for diverse cellular functions such as cell division and signaling in eukaryotic cells.

The time is right to study biological function without stripping systems of their essential eco-evolutionary context.