Browse our Tools and Resources

Page 3 of 81
    1. Cell Biology

    An open-source, high-resolution, automated fluorescence microscope

    Ando Christian Zehrer, Ana Martin-Villalba ... Helge Ewers
    High-quality fluorescence live-cell and single molecule imaging via computer-controlled, user-assembled microscope that fits in incubator, can in large parts be 3D printed and employs open source software and electronics.
    1. Computational and Systems Biology
    2. Neuroscience

    Dissecting muscle synergies in the task space

    David O'Reilly, Ioannis Delis
    A novel network information framework quantifies muscle interactions, characterises their task-relevance, and identifies networks of muscles with similar and complementary functional roles.
    1. Neuroscience

    Towards biologically plausible phosphene simulation for the differentiable optimization of visual cortical prostheses

    Maureen van der Grinten, Jaap de Ruyter van Steveninck ... Yağmur Güçlütürk
    The provided framework based on biological models and clinical literature can aid in the optimization of visual cortical prostheses through computational or behavioral simulation experiments, serving as a flexible tool for computational, clinical, and behavioral neuroscientists working on visual neuroprosthetics.
    1. Neuroscience

    RatInABox, a toolkit for modelling locomotion and neuronal activity in continuous environments

    Tom M George, Mehul Rastogi ... Caswell Barry
    A new python package standardises and simplifies how spatial behaviour and neural representations are modelled in continuous environments.
    1. Neuroscience

    Rabies virus-based barcoded neuroanatomy resolved by single-cell RNA and in situ sequencing

    Aixin Zhang, Lei Jin ... Xiaoyin Chen
    Barcoded rabies virus tracing combined with single-cell RNAseq and in situ sequencing achieves high-throughput retrograde projection mapping and synaptic connectivity mapping at cellular resolution.
    1. Computational and Systems Biology
    2. Immunology and Inflammation

    A kinase to cytokine explorer to identify molecular regulators and potential therapeutic opportunities

    Marina Chan, Yuqi Kang ... Taranjit S Gujral
    KinCytE is a web-based platform that explores kinase-cytokine-driven signaling and its relevance to understanding and treating diseases linked to disruptions in these pathways.
    1. Neuroscience

    osl-dynamics, a toolbox for modeling fast dynamic brain activity

    Chetan Gohil, Rukuang Huang ... Mark W Woolrich
    A generative-model-based, unsupervised learning toolbox for characterizing oscillatory bursting and brain network dynamics in univariate or multivariate time series.
    1. Computational and Systems Biology
    2. Microbiology and Infectious Disease

    Light-inducible protein degradation in E. coli with the LOVdeg tag

    Nathan Tague, Cristian Coriano-Ortiz ... Mary J Dunlop
    The LOVdeg tag is a versatile tool for bacterial optogenetics, offering modular, blue light-inducible protein degradation for a range of synthetic biology and metabolic engineering applications.
    1. Computational and Systems Biology
    2. Genetics and Genomics

    Comparative interactome analysis of α-arrestin families in human and Drosophila

    Kyung-Tae Lee, Inez KA Pranoto ... Jin-Wu Nam
    Unveiling the high-confidence protein–protein interaction networks of human and fly α-arrestins provides insights into conserved and species-specific functional roles depending on their protein domains and motifs.
    1. Genetics and Genomics
    2. Neuroscience

    The gene expression landscape of the human locus coeruleus revealed by single-nucleus and spatially-resolved transcriptomics

    Lukas M Weber, Heena R Divecha ... Stephanie C Hicks
    Spatially-resolved transcriptomics and single-nucleus RNA-sequencing are applied to the human locus coeruleus to characterize the gene expression profiles of norepinephrine (NE) neurons and other cell populations in this critical brain region, with all data made publicly available.