Browse our Tools and Resources

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    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    CRISPR-based functional genomics in human dendritic cells

    Marco Jost, Amy N Jacobson ... Jonathan S Weissman
    A CRISPR-based method enables targeted knockouts and genetic screens in human dendritic cells.
    1. Cell Biology

    A robust method for particulate detection of a genetic tag for 3D electron microscopy

    James Rae, Charles Ferguson ... Robert G Parton
    Development of a new system for gold particle detection of a genetic tag for electron microscopy.
    1. Neuroscience

    Likelihood approximation networks (LANs) for fast inference of simulation models in cognitive neuroscience

    Alexander Fengler, Lakshmi N Govindarajan ... Michael J Frank
    A novel method and software provides researchers with the capability to rapidly, flexibly, and robustly perform Bayesian parameter estimation of theoretically meaningful models in cognitive neuroscience that were heretofore intractable.
    1. Computational and Systems Biology
    2. Ecology

    TRex, a fast multi-animal tracking system with markerless identification, and 2D estimation of posture and visual fields

    Tristan Walter, Iain D Couzin
    Being fast, memory efficient, easy to use, and with powerful integrated tools, TRex will lower barriers of entry into, and enable more ambitious approaches to, the quantitative study of behavior.
    1. Computational and Systems Biology
    2. Microbiology and Infectious Disease

    Integrating taxonomic, functional, and strain-level profiling of diverse microbial communities with bioBakery 3

    Francesco Beghini, Lauren J McIver ... Nicola Segata
    The bioBakery 3 platform enables improved, integrated, and strain-level analysis of microbial communities from large-scale meta-omic data.
    1. Neuroscience

    Visualizing anatomically registered data with brainrender

    Federico Claudi, Adam L Tyson ... Tiago Branco
    Brainrender is an open-source and user-friendly software for combining any type of anatomically registered data into custom interactive 3D renderings.
    1. Neuroscience

    An open-source device for measuring food intake and operant behavior in rodent home-cages

    Bridget A Matikainen-Ankney, Thomas Earnest ... Alexxai V Kravitz
    An open-source behavioral platform allows for operant, feeding, and circadian experiments in rodent home-cages.
    1. Developmental Biology
    2. Neuroscience

    Transcriptional profiling of mouse peripheral nerves to the single-cell level to build a sciatic nerve ATlas (SNAT)

    Daniel Gerber, Jorge A Pereira ... Ueli Suter
    Establishing transcriptional profiles of nerve-inhabitant cells as resource to foster the fundamental understanding of peripheral nerves.
    1. Neuroscience

    Relationship between simultaneously recorded spiking activity and fluorescence signal in GCaMP6 transgenic mice

    Lawrence Huang, Peter Ledochowitsch ... Lu Li
    Simultaneous calcium imaging and cell-attached recording in GCaMP6 transgenic mice in vivo reveals spiking-fluorescence relationship that supports more refined inference of neuronal activities from calcium imaging data.
    1. Immunology and Inflammation
    2. Neuroscience

    Development and characterization of a chronic implant mouse model for vagus nerve stimulation

    Ibrahim T Mughrabi, Jordan Hickman ... Stavros Zanos
    Long-term, dose-controlled vagus nerve stimulation (VNS) is feasible in mice using a multi-lab validated implantation procedure, allowing therapeutic testing of VNS in many disease models.