The International Brain Laboratory, Valeria Aguillon-Rodriguez ... Anthony M Zador
A standard for complex mouse behavior that can be successfully reproduced across laboratories, along with open-access data and tools to implement provide a resource for reproducibility through collaborative open-science approaches.
Immunohistochemical labeling of antigens deep within mouse brain tissue sections was achieved without the need for lipid permeabilization, thereby preserving tissue ultrastructure and enabling correlative light and electron microscopy studies.
A fully automated workflow for high-throughput mouse behavioral and optogenetic experiments in homecage reveals involvement of brain regions in tactile decision-making.
Shannon M Walsh, Ryan M Sheridan ... Beth Ann Jiron Tamburini
Antigen-phosphorothioate DNA conjugation provides a vaccination strategy where stable barcodes facilitate the detection and quantification of antigen using single-cell RNA sequencing.
James W Opzoomer, Jessica A Timms ... Shahram Kordasti
ImmunoCluster permits nonspecialist users to interrogate liquid and imaging mass, and flow cytometry datasets, resolving novel layers of cellular heterogeneity and insight, as well as producing publishable outputs and figures.
How large-scale single mosquito metatranscriptomics can define the mosquito’s complex microbiota and its blood meal sources, and contribute critical epidemiological information needed to control vector borne disease transmission, is shown.
Alexander Fengler, Lakshmi N Govindarajan ... Michael J Frank
A novel method and software provides researchers with the capability to rapidly, flexibly, and robustly perform Bayesian parameter estimation of theoretically meaningful models in cognitive neuroscience that were heretofore intractable.
