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    1. Neuroscience

    The inevitability and superfluousness of cell types in spatial cognition

    Xiaoliang Luo, Robert M Mok, Bradley C Love
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Incomplete
    1. Evolutionary Biology

    Parallel HIV-1 fitness landscapes shape viral dynamics in humans and macaques that develop broadly neutralizing antibodies

    Kai S Shimagaki, Rebecca M Lynch, John P Barton
    Fitness constraints on the HIV envelope protein are highly similar in humans and rhesus macaques, emphasizing the utility of macaque models of infection and antibody development.
    1. Developmental Biology

    A tissue boundary orchestrates the segregation of inner ear sensory organs

    Ziqi Chen, Magdalena Żak ... Nicolas Daudet
    A boundary between the sensory and nonsensory domains contains cells that undergo a series of morphological changes and form basal constriction to separate the segregating inner ear sensory organs.
    1. Neuroscience

    Eye-specific differences in active zone addition during synaptic competition in the developing visual system

    Chenghang Zhang, Tarlan Vatan, Colenso M Speer
    Eye-specific differences in presynaptic release site addition and clustering correlate with axonal segregation outcomes during retinogeniculate refinement in the mouse.
    1. Physics of Living Systems
    2. Structural Biology and Molecular Biophysics

    Roles of the membrane-binding motif and the C-terminal domain of RNase E in localization and diffusion in E. coli

    Laura Troyer, Yu-Huan Wang ... Sangjin Kim
    Single-molecule imaging uncovers how distinct membrane-binding motifs and the intrinsically disordered C-terminal domain control RNase E’s membrane association and diffusion, linking structural divergence to RNA-processing dynamics in bacteria.
    1. Neuroscience

    Rhythmic sampling and competition of target and distractor in a motion detection task

    Changhao Xiong, Nathan M Petro ... Mingzhou Ding
    Spatially and temporally overlapping target and distractor are both rhythmically sampled at ~1 Hz, and the phase relationship between target sampling and distractor sampling predicts behavior.
    1. Neuroscience

    Glaucoma-associated Optineurin mutations increase transcellular degradation of mitochondria in a vertebrate optic nerve

    Yaeram Jeong, Chung-ha O Davis ... Nicholas Marsh-Armstrong
    Increased transfer of axonal mitochondria to optic nerve astrocytes after expression of glaucoma-associated Optineurin variants suggest that increased transcellular degradation of axonal mitochondria may play a causative role in at least some forms of glaucoma.
    1. Neuroscience

    Extracting Value Coding Features from Individual Serotonin Neurons

    Emerson F Harkin, Jean-Claude Béïque, Richard Naud
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete