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    1. Ecology
    2. Evolutionary Biology

    Rapid riparian ecosystem recovery in low-latitudinal North China following the end-Permian mass extinction

    Wenwei Guo, Li Tian ... Jinnan Tong
    In low-latitude North China, riparian ecosystems began to recover 2–3 million years after the end-Permian mass extinction.
    1. Biochemistry and Chemical Biology
    2. Computational and Systems Biology

    Identification and classification of ion channels across the tree of life provide functional insights into understudied CALHM channels

    Rahil Taujale, Sung Jin Park ... Natarajan Kannan
    An evolution-guided framework is proposed to accelerate the discovery and therapeutic targeting of understudied dark channels by integrating sequence, structure, and functional data from diverse organisms.
    1. Genetics and Genomics

    Mapping of in vivo cleavage sites uncovers a major role for yeast RNase III in regulating protein-coding genes

    Lee-Ann Notice-Sarpaning, Mathieu Catala ... Ambro van Hoof
    The yeast Drosha homolog Rnt1 has a major role in mRNA degradation.
    1. Neuroscience

    Revealing the benefit of eye motion for acuity under emulated cone loss

    Hannah K Doyle, James Fong ... Austin Roorda
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Cell size modulates ferroptosis susceptibility

    Evgeny Zatulovskiy, Magdalena B Murray ... Jan M Skotheim
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Neuroscience

    Modulation of human dorsal root ganglion neuron excitability by Nav1.7 inhibition

    Akie Fujita, Sooyeon Jo ... Bruce P Bean
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Neuroscience

    Tactile localization of the breast, areola, and nipple

    Katie H Long, Emily E Fitzgerald ... Charles M Greenspon
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Convincing
    1. Neuroscience

    Learned and inferred valence arise from interactions between stable and dynamic subnetworks

    Marc E Normandin, Pedro M Ogallar ... Isabel A Muzzio
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Chromosomes and Gene Expression
    2. Immunology and Inflammation

    Genome Restructuring around Innate Immune Genes in Monocytes in Alcohol-associated Hepatitis

    Adam Kim, Megan R McMullen ... Srinivasan Dasarathy
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Incomplete
    1. Genetics and Genomics

    Stranded short nascent strand sequencing reveals the topology of DNA replication origins in Trypanosoma brucei

    Slavica Stanojcic, Bridlin Barckmann ... Yvon Sterkers
    Replication origins in Trypanosoma brucei integrate multiple features previously described individually in opisthokonts, revealing a unified structural topology built from strand-specific nucleotide composition, G‑quadruplex enrichment, and distinctive nucleosome patterns.
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