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Page 18 of 1,875
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Defining the chromatin-associated protein landscapes on Trypanosoma brucei repetitive elements using synthetic TALE proteins

    Roberta Carloni, Tadhg Devlin ... Robin C Allshire
    Synthetic proteins designed to bind specific repetitive DNA sequences in the Trypanosoma brucei genome allow the identification of proteins enriched over different DNA elements.
    1. Cell Biology

    Large-scale identification of plasma membrane repair proteins revealed spatiotemporal cellular responses to plasma membrane damage

    Yuta Yamazaki, Keiko Kono
    Proteome-scale visual screening in budding yeast provides a functional catalog of plasma membrane repair proteins and reveals the coordinated cellular responses at the bud tip and the damage site.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    EPB41L4A-AS1 long noncoding RNA acts in both cis- and trans-acting transcriptional regulation and controls nucleolar biology

    Alan Monziani, Juan Pablo Unfried ... Igor Ulitsky
    EPB41L4A-AS1, a highly expressed snoRNA host long noncoding RNA, has multiple functions, positive regulation in cis of the EPB41L4A gene and a trans-acting role in supporting proper nucleolar biology.
    1. Neuroscience

    Movie reconstruction from mouse visual cortex activity

    Joel Bauer, Troy W Margrie, Claudia Clopath
    Naturalistic movie reconstruction from mouse visual cortex activity achieves high spatial and temporal fidelity.
    1. Developmental Biology
    2. Genetics and Genomics

    Nup107 is a crucial regulator of torso-mediated metamorphic transition in Drosophila melanogaster

    Jyotsna Kawadkar, Pradyumna Ajit Joshi, Ram Kumar Mishra
    Y-complex nucleoporin, Nup107, can regulate ecdysone production by affecting the transcription of Halloween genes and levels of RTK receptor, torso, for the metamorphic transition from larva to pupa.
    1. Neuroscience

    Designing optimal perturbation inputs for system identification in neuroscience

    Mikito Ogino, Daiki Sekizawa ... Masafumi Oizumi
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    • Incomplete
    1. Evolutionary Biology

    Inference of germinal center evolutionary dynamics via simulation-based deep learning

    Duncan K Ralph, Athanasios G Bakis ... Frederick A Matsen
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Compelling
    1. Cell Biology

    Desert Hedgehog mediates stem Leydig cell differentiation through Ptch2/Gli1/Sf1 signaling axis

    Changle Zhao, Yongxun Chen ... Jing Wei
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Neuroscience

    Descending locus coeruleus noradrenergic signaling to spinal astrocyte subset is required for stress-induced mechanical pain hypersensitivity

    Riku Kawanabe-Kobayashi, Sawako Uchiyama ... Makoto Tsuda
    Stress activates a locus coeruleus–spinal dorsal horn noradrenergic circuit that drives mechanical pain hypersensitivity through Hes5-positive astrocytes.
    1. Computational and Systems Biology
    2. Microbiology and Infectious Disease

    Automated genome mining predicts structural diversity and taxonomic distribution of peptide metallophores across bacteria

    Zachary L Reitz, Bita Pourmohsenin ... Marnix H Medema
    Automated detection of metallophore biosynthesis reveals that metal-chelating non-ribosomal peptides are widespread, chemically diverse, and deeply rooted in bacterial evolution.
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