In statistical fine-mapping, signals stable across stratified subgroups can capture functionally important loci missed by covariate adjustment approaches, and prioritizing agreement between both approaches enhances functional variant discovery.
Antoine Bouyeure, Daniel Pacheco-Estefan ... Nikolai Axmacher
Fear updating relies on a flexible shift from generalized to item-specific, context-bound neural representations, revealing how the brain adapts to changing threat contingencies and why fear can return.