Browse the latest research

Page 19 of 1,888
    1. Developmental Biology
    2. Genetics and Genomics

    Single-cell co-mapping reveals relationship between chromatin state and gene expression in early zebrafish development

    Vivek Bhardwaj, Alberto Griffa ... Alexander van Oudenaarden
    A robust and quantitative map links chromatin modification and gene expression of cells during zebrafish embryogenesis.
    1. Cell Biology

    Prior cocaine use disrupts identification of hidden states by single units and neural ensembles in orbitofrontal cortex

    Wenhui Zong, Lauren Mueller ... Geoffrey Schoenbaum
    Rats with a history of cocaine use exhibited prolonged encoding of idiosyncratic task features in orbitofrontal cortex and a reduced ability to compress such features to identify underlying hidden states.
    1. Structural Biology and Molecular Biophysics

    PPIscreenML is a method for structure-based screening of protein-protein interactions using AlphaFold

    Victoria Mischley, Johannes Maier ... John Karanicolas
    PPIscreenML is a rigorously benchmarked method that uses AlphaFold2 to screen for interacting protein pairs, and it provides superior performance to other available methods.
    1. Microbiology and Infectious Disease

    Antibiotic potentiation and inhibition of cross-resistance in pathogens associated with cystic fibrosis

    Nikol Kadeřábková, R Christopher D Furniss ... Despoina AI Mavridou
    Targeting disulfide bond formation disables multiple antibiotic resistance mechanisms and prevents cross-protection between pathogens associated with cystic fibrosis lung infections, restoring antibiotic efficacy in polymicrobial settings.
    1. Neuroscience

    Brain-wide mapping of layer-specific functional connectivity in the human cortex at 3T using draining-vein-suppressed fMRI

    Wei-Tang Chang, Weili Lin, Kelly S Giovanello
    A velocity-nulled 3T GE-EPI fMRI method enabling 0.9-mm whole-brain imaging that suppresses vascular contamination and reliably maps layer-specific functional connectivity in human cortex.
    1. Developmental Biology
    2. Genetics and Genomics

    In situ mutational screening and CRISPR interference define apterous cis-regulatory inputs during compartment boundary formation

    Gustavo Aguilar, Michèle Sickmann ... Martin Müller
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Compelling
    1. Chromosomes and Gene Expression

    mRNA Imprinting: transcription apparatus can remotely control cytoplasmic post-transcriptional mechanisms by dozens of proteins

    Shira Urim, Artyom Artamov ... Mordechai Choder
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Developmental Biology

    Cellular basis of accelerated whole-tooth regeneration

    Talha Mubeen, Haowen He ... Jeffrey T Streelman
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    • Incomplete