Mahdiyar Shahbazi, Olivier Codol ... Paul L Gribble
Recurrent neural network models trained on a novel motor skill exhibit a persistent shift in preparatory activity that enables faster relearning, without cognitive or contextual cues.
A biologically plausible reinforcement learning model that integrates associative memory and hippocampal remapping explains context-dependent flexible behavior, neural dynamics, and psychosis-related symptoms.
Lamina I projection neurons that respond selectively to skin cooling receive monosynaptic input from Trpm8-expressing primary afferents and innervate brain regions involved in perception of cold and cold defence mechanisms.
The Drosophila ryanodine receptor plays a conserved role in setting functional and structural muscle properties, regulates embryonic muscle development and could be used to assess the impact of human RYR1 mutations.
Marco Nigro, Lucas Silva Tortorelli ... Hongdian Yang
Inhibiting locus coeruleus input to the medial prefrontal cortex in mice impaired task performance, affected the tuning of single cortical neurons and disrupted population dynamics and encoding capacity during attentional switching.