Browse the latest research

Page 19 of 1,869
    1. Computational and Systems Biology
    2. Neuroscience

    Deep neural networks to register and annotate cells in moving and deforming nervous systems

    Adam A Atanas, Alicia Kun-Yang Lu ... Steven W Flavell
    New machine vision tools are used to align densely packed cells recorded from live, deforming tissues and automatically annotate the identities of the recorded cell types.
    1. Neuroscience

    A three-dimensional immunofluorescence atlas of the brain of the hackled-orb weaver spider, Uloborus diversus

    Gregory Artiushin, Abel Corver, Andrew Gordus
    A detailed annotation of anatomical brain structures (some novel) of the spider Uloborus diversus is provided based on a three-dimensional immunostain atlas.
    1. Microbiology and Infectious Disease

    Neutralizing human monoclonal antibodies that target the PcrV component of the type III secretion system of Pseudomonas aeruginosa act through distinct mechanisms

    Jean-Mathieu Desveaux, Eric Faudry ... Pascal Poignard
    Human antibodies isolated from cystic fibrosis patients against PscF and PcrV of the Pseudomonas aeruginosa Type 3 Secretion System reveal that anti-PcrV antibodies inhibit secretion through distinct mechanisms.
    1. Neuroscience

    Control of innate olfactory valence by segregated cortical amygdala circuits

    James R Howe, Chung-Lung Chan ... Cory M Root
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Convincing
    1. Cell Biology

    EOLA1, a novel mitochondria-localized protein critical for heart functions via regulating mitochondrial translation

    Xiaoyan Shi, Yangyi Zhang ... Hao Chen
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Microbiology and Infectious Disease

    4-aminoquinolines block heme iron reactivity and interfere with artemisinin action

    Melissa R Rosenthal, Daniel E Goldberg
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Genetics and Genomics

    SETDB1 enables development beyond cleavage stages by extinguishing the MERVL-driven two-cell totipotency transcriptional program in the mouse embryo

    Tie-Bo Zeng, Zhen Fu ... Piroska E Szabó
    Conditional genetics and single-embryo RNA-seq show that SETDB1 extinguishes the transient, retroelement-driven transcriptional programs of the totipotent two-cell state to facilitate the exit from totipotency and ensure preimplantation development.
    1. Neuroscience

    Frictional instabilities as an alternative to friction coefficient in fine touch perception

    Maryanne Derkaloustian, Pushpita Bhattacharyya ... Charles B Dhong
    To study fine touch, selecting samples based on how many mechanical instabilities they can form is more predictive than using the friction coefficient, which has been the default choice.
    1. Neuroscience

    Single molecule counting detects low-copy glycine receptors in hippocampal and striatal synapses

    Serena Camuso, Yana Vella ... Christian G Specht
    Synapses in the forebrain were thought of as purely GABAergic, yet they contain minute numbers of glycine receptors, often in the single digits.