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Page 19 of 1,818
    1. Neuroscience

    Acquisition phase-specific contribution of climbing fiber transmission to cerebellum-dependent motor memory in mice

    Jewoo Seo, Seung Ha Kim ... Sang Jeong Kim
    Climbing fiber activity gates the acquisition phase of motor learning but becomes nonessential for memory consolidation or performance once proficiency is achieved.
    Version of Record
    Short Report
    • Valuable
    • Incomplete
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Opening and closing of a cryptic pocket in VP35 toggles it between two different RNA-binding modes

    Upasana L Mallimadugula, Matthew A Cruz ... Gregory R Bowman
    The cryptic pocket is critical for one of the VP35 protein's functions and therefore is likely under selective pressure.
    1. Genetics and Genomics

    Gene expression variation across genetically identical individuals predicts reproductive traits

    Amy K Webster, John H Willis ... Patrick C Phillips
    Differences among genetically identical individuals can be explained using expression levels of just a handful of genes, suggesting that environmental variation can be functionally analyzed.
    1. Computational and Systems Biology

    The Product neutrality function defining genetic interactions emerges from mechanistic models of cell growth

    Lucas Fuentes Valenzuela, Paul Francois, Jan M Skotheim
    Coarse-grained models of cellular growth and high-throughput empirical genetic data support the Product neutrality function in which a double-mutant fitness is the product of single-mutant fitnesses.
    1. Neuroscience

    Astrocytic modulation of population encoding in mouse visual cortex via GABA transporter 3 revealed by multiplexed CRISPR/Cas9 gene editing

    Jiho Park, Grayson O Sipe ... Mriganka Sur
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Cell Biology
    2. Developmental Biology

    Sulfation affects apical extracellular matrix organization during development of the Drosophila embryonic salivary gland tube

    J Luke Woodward, Jeffrey Matthew ... SeYeon Chung
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Microbiology and Infectious Disease

    Bacteria detect neutrophils via a system that responds to hypochlorous acid and flow

    Ilona P Foik, Runhang Shu ... Albert Siryaporn
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Cell Biology

    Megakaryocytes assemble a three-dimensional cage of extracellular matrix that controls their maturation and anchoring to the vascular niche

    Claire Masson, Cyril Scandola ... Anita Eckly
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Compelling
    1. Neuroscience
    2. Computational and Systems Biology

    Morphogenesis and morphometry of brain folding patterns across species

    Sifan Yin, Chunzi Liu ... L Mahadevan
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Immunology and Inflammation
    2. Stem Cells and Regenerative Medicine

    IL-27 limits HSPC differentiation during infection and protects from stem cell exhaustion

    Daniel L Aldridge, Zachary Lanzar ... Christopher A Hunter
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
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