Browse the latest research

Page 19 of 1,867
    1. Neuroscience

    Mouse sensorimotor cortex reflects complex kinematic details during reaching and grasping

    Harrison A Grier, Sohrab Salimian, Matthew T Kaufman
    Mouse primary motor and somatosensory cortices contain detailed information about the many time-varying arm and paw joint angles during reaching and grasping, implying a 'low-level' role in controlling these movements.
    1. Cell Biology
    2. Structural Biology and Molecular Biophysics

    Accessibility of the unstructured α-tubulin C-terminal tail is controlled by microtubule lattice conformation

    Takashi Hotta, Morgan L Pimm ... Kristen J Verhey
    Three newly developed biosensors demonstrate that the C-terminal tail of α-tubulin does not freely extend from the microtubule surface as widely thought, but rather is inaccessible along most microtubules in cells.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    EPB41L4A-AS1 long noncoding RNA acts in both cis- and trans-acting transcriptional regulation and controls nucleolar biology

    Alan Monziani, Juan Pablo Unfried ... Igor Ulitsky
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Neuroscience

    Detecting Regime Shifts: Neurocomputational Substrates for Over- and Underreactions to Change

    Mu-Chen Wang, George Wu, Shih-Wei Wu
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Solid
    1. Medicine

    Magnesium isoglycyrrhizinate alleviates alcohol-associated liver disease through targeting HSD11B1

    Lu Xiao, Lu Li ... Jia Xiao
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Immunology and Inflammation

    An IL-21R hypomorph circumvents functional redundancy to define STAT1 signaling in germinal center responses

    Christoph Jandl, Joanna Warren ... Cecile King
    Not revised
    Reviewed Preprint v1
    • Incomplete
    1. Cell Biology

    Single-cell lineage tracing identifies hemogenic endothelial cells in the adult mouse bone marrow

    Jing-Xin Feng, Mei-Ting Yang ... Giovanna Tosato
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Biochemistry and Chemical Biology

    Transforming a Fragile Protein Helix into an Ultrastable Scaffold via a Hierarchical AI and Chemistry Framework

    Jun Qiu, Guojin Tang ... Peng Zheng
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Neuroscience

    Alpha-Band Phase Modulates Perceptual Sensitivity by Changing Internal Noise and Sensory Tuning

    April Pilipenko, Alexandra Mcgowan, Jason Samaha
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Distinct chromatin regulators downmodulate meiotic axis protein deposition and DNA break induction at chromosome ends

    Adhithi R Raghavan, Kieron May ... Andreas Hochwagen
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete