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A validated, open design brings programmable non-invasive photostimulation of multiple cortical areas in behaving mice to labs without expertise in optics or software design.

Salinity does not alter nutrient resorption efficiency, which is instead shaped by phylogeographic history and latitude.

Small brown planthopper infestation drives rice glucose redistribution to boost its own reproduction and insecticide tolerance.

gSWITCH identifies dynamic lineage switch genes and reveals BCL11A as an evolutionarily conserved regulator whose restoration rescues age-impaired oligodendrocyte progenitor cell differentiation.

Distinct effects of peptidomimetic inhibitors and ebselen on SARS-CoV-2 main protease dimerization reveal new strategies for antiviral drug design.

High-resolution structural information can be recovered from proteins well below the conventional cryo-electron microscopy size range, substantially extending the range of complexes accessible to structural analysis.

Within the locomotor network of the Drosophila embryo, connected elements, from premotor interneuron to muscle, respond differentially to a critical period perturbation, suggesting a sequence of adjustment.

Mid-zone hepatocytes transiently pause proliferation through the Atf4-Chop-Btg2 axis to prioritize survival over regeneration during early acute liver injury.