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It is shown that the absence of the centrosome protein ninein provokes premature ossification during mouse development, due to a defect in the fusion of precursor cells into syncytial osteoclasts.

Uninterrupted CAG repeat length determines onset age in Huntington's disease, and therefore, base editing strategies to generate CAA interruption offer new therapeutic opportunities as they diminish the disease-causing mutation.

Comparative transcriptome analyses of human placenta reveal regulatory divergence between native highlanders and lowland immigrants living at high altitude, and a sex-biased pattern of genetic adaptation.

When used to capture fluid cognition, Brain Age likely fails to add substantially more information over and above chronological age and could miss up to around one-third of the variation.

A novel behavioural pipeline enables the quantitative analysis of the onset of movement in Drosophila embryos revealing that a microRNA modulates this process through regulatory effects in the sensory system.