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    1. Cell Biology
    2. Developmental Biology

    The Drosophila EcR-Hippo component Taiman promotes epithelial cell fitness by control of the Dally-like glypican and Wg gradient

    Colby K. Schweibenz, Victoria C. Placentra, Kenneth H. Moberg
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Neuroscience

    Homeostatic regulation of rapid eye movement sleep by the preoptic area of the hypothalamus

    John J Maurer, Alexandra Lin ... Shinjae Chung
    Preoptic area of the hypothalamus is important for the homeostatic regulation of rapid eye movement sleep.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Structural characterization of ligand binding and pH-specific enzymatic activity of mouse Acidic Mammalian Chitinase

    Roberto Efraín Díaz, Andrew K Ecker ... James S Fraser
    Biochemical and structural investigations of the pH adaptability of mouse Acidic Mammalian Chitinase offer insights for designing enhanced enzyme variants that can function in both lung and gut.
    1. Immunology and Inflammation

    Expression of modified FcγRI enables myeloid cells to elicit robust tumor-specific cytotoxicity

    Leen Farhat-Younis, Manho Na ... Yaron Carmi
    Genetic engineering of murine myeloid cells reveals the challenges in ectopic expression of chemiric receptors and provides a novel framework to endow them with tumor-specific cytotoxic ability.
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    Toxin-based screening of C-terminal tags in Escherichia coli reveals the exceptional potency of ssrA-like degrons

    Patrick C. Beardslee, Karl R. Schmitz
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Cell Biology
    2. Genetics and Genomics

    Temporally controlled nervous system-to-gut signaling bidirectionally regulates longevity in C. elegans

    Lingxiu Xu, Chengxuan Han ... Jianfeng Liu
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Developmental Biology

    Identification and characterization of intermediate states in mammalian neural crest cell epithelial to mesenchymal transition and delamination

    Ruonan Zhao, Emma L Moore ... Paul A Trainor
    Epithelial to mesenchymal transition (EMT) is a continuous process, in which the transition or intermediate states can be molecularly and spatially defined, shedding new light on development and disease EMT.
    1. Cancer Biology

    A chronic signaling TGFb zebrafish reporter identifies immune response in melanoma

    Haley R Noonan, Alexandra M Thornock ... Leonard I Zon
    An in vivo reporter of TGFb signaling in zebrafish reveals that melanoma cells undergoing chronic TGFb signaling up-regulate extracellular matrix genes, down-regulate IFN, and are preferentially phagocytosed by macrophages compared to non-TGFb responsive melanoma cells.
    1. Computational and Systems Biology
    2. Neuroscience

    Correction: Statistical context dictates the relationship between feedback-related EEG signals and learning

    Matthew R Nassar, Rasmus Bruckner, Michael J Frank
    1. Neuroscience

    Distance and grid-like codes support the navigation of abstract social space in the human brain

    Zilu Liang, Simeng Wu ... Chao Liu
    New data provides partial evidence that abstract social knowledge adopts a similar encoding scheme as spatial cognitive maps in the human brain.
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