Browse the latest research

Page 46 of 1,893
    1. Cell Biology
    2. Neuroscience

    CUTS RNA Biosensor for the Real-Time Detection of TDP-43 Loss-of-Function

    Longxin Xie, Jessica Merjane ... Christopher J Donnelly
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Neuroscience

    Synaptic vesicle undocking induces low frequency depression

    Melissa Silva, Federico F Trigo ... Alain Marty
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Convincing
    1. Neuroscience

    A multi-resolution imaging and analysis pipeline for comparative circuit reconstruction in insects

    Valentin Gillet, Marcel E Sayre ... Stanley Heinze
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    • Incomplete
    1. Neuroscience

    Mood computational mechanisms underlying increased risk behavior in adolescent suicidal patients

    Zhihao Wang, Tian Nan ... Bastien Blain
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Microbiology and Infectious Disease

    A Novel Rapid Host Cell Entry Pathway Determines Intracellular Fate of Staphylococcus aureus

    Marcel Rühling, Fabio Schmelz ... Martin J Fraunholz
    Revised
    Reviewed Preprint v4
    Updated
    • Valuable
    • Solid
    1. Cancer Biology

    JAK-STAT Pathway Heterogeneity Governs Immunotherapy Response in Breast Cancer

    Jianbo Zhou, Heng Zhang ... Fu Peng
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Convincing
    1. Physics of Living Systems
    2. Structural Biology and Molecular Biophysics

    Detecting directed motion and confinement in single-particle trajectories using hidden variables

    François Simon, Guillaume Ramadier ... Lucien E Weiss
    Exatrack is a framework for analyzing Brownian, directed, and confined motion using a hidden-variable probabilistic model to extract physical insight into particle diffusion.
    1. Chromosomes and Gene Expression
    2. Computational and Systems Biology

    DNA O-MAP uncovers the molecular neighborhoods associated with specific genomic loci

    Yuzhen Liu, Christopher D McGann ... Devin K Schweppe
    DNA O-MAP enables proximity labeling at specific genomic loci in fixed cells using programmable oligonucleotides, revealing locus-proximal proteomes and chromatin interactions without genetic modification.
    1. Neuroscience

    Increased reluctant vesicles underlie synaptic depression by GPR55 in axon terminals of rat cerebellar Purkinje cells

    Takuma Inoshita, Shin-ya Kawaguchi
    Direct presynaptic patch-clamp recording and fluorescent imaging of the vesicular release demonstrate that a non-canonical cannabinoid receptor GPR55 deprives readily releasable vesicles of competency in cerebellar Purkinje cell axons.
    1. Biochemistry and Chemical Biology
    2. Computational and Systems Biology

    Investigating the native functions of [NiFe]-CODH through genomic context analysis

    Maximilian Böhm, Henrik Land
    Genomic neighborhood signatures delineate catalytic versus putative regulatory CODH clades, establishing a framework for predicting enzyme functionality and guiding discovery of biocatalysts for CO2 reduction.