A single conserved residue – histidine 12 – confers pH-sensitive DNA binding to the Salmonella Typhimurium SPI-2 transcriptional regulator SsrB, thereby regulating Salmonella virulence.
Increasing the intra-species phenotypic diversity of a plant-beneficial bacterium effectively improves probiotic consortium functioning and plant growth promotion in agricultural systems.
C Kim, Benjamin Chen ... RECOVER Mechanistic Pathways Task Force
Collaborative and mutually beneficial patient-provider-researcher relationships are crucial in achieving success in understanding and treating long COVID.
The apical polarity protein CRB3 is crucial for regulating vesicle trafficking in γ-tubulin ring complex assembly during ciliogenesis and cilium-related Hedgehog and Wnt signaling pathways in tumorigenesis.
Investigations of the reaction center (RC)-light harvesting (LH) complex from an ancient chlorosome-less anoxygenic phototroph Roseiflexus castenholzii reveal the structural basis by which carotenoids assembly regulates the architecture and quinone exchange of bacterial RC-LH complex.
FOXP2, encoding a forkhead-box transcription factor regarded as vital to proper development of human speech, was revealed to have an oncogenic potential and activate MET signaling in prostate cancer.