Microbiology and Infectious Disease

Latest articles

1. 1. Microbiology and Infectious Disease

   The PPE2 protein of Mycobacterium tuberculosis is responsible for the development of hyperglycemia and insulin resistance during tuberculosis

   Manoj Kumar Bisht, Vandana Maurya ... Sangita Mukhopadhyay
2. 1. Microbiology and Infectious Disease

   Heterogeneity of genetic sequence within quasi-species of influenza virus revealed by single-molecule sequencing

   Kenji Tamao, Hiroyuki Noji, Kazuhito Tabata

   High-accuracy single-molecule unique molecular identifier sequencing reveals non-random, biologically driven mutation heterogeneity within influenza quasi-species, enabling precise profiling of intra-host viral evolutionary potential.
3. 1. Cell Biology
   2. Microbiology and Infectious Disease

   Decoding the biogenesis of HIV-induced CPSF6 puncta and their fusion with nuclear speckles

   Chiara Tomasini, Celine Cuche ... Francesca Di Nunzio

   HIV hijacks SRRM2 to enlarge nuclear speckles, stabilizing CPSF6 puncta and promoting efficient viral replication.
4. 1. Microbiology and Infectious Disease

   A dual role for PGLYRP1 in host defense and immune regulation during B. pertussis infection

   David M Rickert, Sasha Cardozo ... Ciaran Skerry
5. 1. Genetics and Genomics
   2. Microbiology and Infectious Disease

   Deletion of the moeA gene in Flavobacterium IR1 drives structural color shift from green to blue and alters polysaccharide metabolism

   Álvaro Escobar Doncel, Constantinos Patinios ... Colin J Ingham

   Disrupting a single molybdenum cofactor gene allowed us to connect metabolic regulation of complex carbohydrates with cell organization, enabling genetic tuning of bacterial structural color for biomaterial applications.
6. 1. Genetics and Genomics
   2. Microbiology and Infectious Disease

   Neisseria gonorrhoeae LIN codes provide a robust, multi-resolution lineage nomenclature

   Anastasia Unitt, Made A Krisna ... Odile B Harrison

   LIN code offers a reliable framework for classifying gonococcal population structure, enabling straightforward exploration of isolate relationships, from broad superlineage divisions to minute single allele differences.
7. 1. Microbiology and Infectious Disease
   2. Structural Biology and Molecular Biophysics

   Evolution of a fuzzy ribonucleoprotein complex in viral assembly

   Huaying Zhao, Tiansheng Li ... Peter Schuck

   The stability of ribonucleoprotein complexes of SARS-CoV-2 nucleocapsid proteins differs among variants of concern and the viral evolution of nucleocapsid protein can be understood in the framework of fuzzy complexes.
8. 1. Immunology and Inflammation
   2. Microbiology and Infectious Disease

   Glycosylated IgG antibodies contribute to the recovery of haemorrhagic fever with renal syndrome patients

   Chuansong Quan, Lu Wang ... Haifeng Hou

   Increased fucosylated IgG and reduced bisecting GlcNAc during HTNV convalescence may promote rapid recovery from hemorrhagic fever with renal syndrome.
9. 1. Microbiology and Infectious Disease

   A system for functional studies of the major virulence factor of malaria parasites

   Jakob Cronshagen, Johannes Allweier ... Tobias Spielmann

   The generation of malaria parasites expressing only one of the multiple variants of their most important virulence factor enables the study of different aspects of this virulence factor.
10. 1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Phospholipid scramblase 1 (PLSCR1) regulates interferon-lambda receptor 1 (IFN-λR1) and IFN-λ signaling in influenza A virus (IAV) infection

    Alina Xiaoyu Yang, Lisa Ramos-Rodriguez ... Yang Zhou

    PLSCR1 is an IFN-λ-stimulated gene that enhances IFN-λR1 expression at both transcriptional and protein level, highlighting the potential for targeting PLSCR1 pathways in anti-influenza therapy.