Neuroscience

Neuroscience

eLife reviews research including brain function, neuronal circuits, synapses, sensory processing and motor pattern generation. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Neuroscience

    The interplay between homeostatic synaptic scaling and homeostatic structural plasticity maintains the robust firing rate of neural networks

    Han Lu, Sandra Diaz-Pier ... Andreas Vlachos
    A biphasic structural plasticity rule interacts with homeostatic synaptic scaling to maintain firing rate homeostasis in neural networks.
    1. Neuroscience

    Cestode larvae excite host neuronal circuits via glutamatergic signalling

    Anja de Lange, Hayley Tomes ... Joseph V Raimondo
    Parasitic tapeworm larvae release glutamate and other excitatory molecules that can directly excite brain neurons.
    1. Neuroscience

    Multifaceted role of galanin in brain excitability

    Nicolas N Rieser, Milena Ronchetti ... Stephan CF Neuhauss
    The neuropeptide galanin modulates whole-brain activity and stress responses in zebrafish, revealing a complex, receptor-dependent role in seizure regulation with implications for epilepsy, and related neurological disorders.
    1. Neuroscience

    A neural network model that generates salt concentration memory-dependent chemotaxis in Caenorhabditis elegans

    Masakatsu Hironaka, Tomonari Sumi
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Biochemistry and Chemical Biology
    2. Neuroscience

    Modular DNA Barcoding of Nanobodies Enables Multiplexed in situ Protein Imaging and High-throughput Biomolecule Detection

    Shilin Zhong, Ruiyu Wang ... Minmin Luo
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Compelling
    1. Neuroscience

    Intrinsic dynamic shapes responses to external stimulation in the human brain

    Maximilian Nentwich, Marcin Leszczynski ... Lucas C Parra
    A new computational model improves estimation of Granger connectivity by removing spurious effects of external inputs, and estimation of linear encoding models by removing spurious effects of recurrent connections.
    1. Neuroscience
    2. Computational and Systems Biology

    Assemblies, synapse clustering, and network topology interact with plasticity to explain structure-function relationships of the cortical connectome

    András Ecker, Daniela Egas Santander ... Michael W Reimann
    A new framework for exploring the mechanisms underlying learning in cortical microcircuits is established.
    1. Neuroscience
    2. Physics of Living Systems

    Responses to membrane potential-modulating ionic solutions measured by magnetic resonance imaging of cultured cells and in vivo rat cortex

    Kyeongseon Min, Sungkwon Chung ... Jang-Yeon Park
    Magnetic resonance imaging, through its sensitivity to ionic environments that modulate membrane potential, enables noninvasive assessment of biological systems.
    1. Neuroscience

    Elucidating the selection mechanisms in context-dependent computation through low-rank neural network modeling

    Yiteng Zhang, Jianfeng Feng, Bin Min
    Mechanistic modeling with low-rank recurrent networks uncovers the relationship between network connectivity, neural dynamics, and selection modulation mechanisms in context-dependent computation.
    1. Neuroscience

    Sequence action representations contextualize during early skill learning

    Debadatta Dash, Fumiaki Iwane ... Leonardo G Cohen
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Solid

Highlights

    1. Neuroscience

    Making a lasting impression

    Rochelle Ackerley, Roger H Watkins

Senior editors

  1. André F Marquand
    Donders Institute, Radboud University / King's College London, Netherlands
  2. Panayiota Poirazi
    Foundation for Research and Technology–Hellas, Greece
  3. Kenton J Swartz
    National Institute of Neurological Disorders and Stroke, NIH, United States
  4. See more editors