Neuroscience

Neuroscience

eLife reviews research including brain function, neuronal circuits, synapses, sensory processing and motor pattern generation. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Neuroscience

    AFD Thermosensory Neurons Mediate Tactile-Dependent Locomotion Modulation in C. elegans

    Manuel Rosero, Jihong Bai
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Neuroscience

    Direction and orientation preferences in mouse superior colliculus and its retinal inputs exhibit a topography of cardinal biases atop locally mixed tuning

    Zhewen He, María Florencia González Fleitas ... Sylvia Schröder
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Neuroscience

    A mechanistic theory of planning in prefrontal cortex

    Kristopher T Jensen, Peter Doohan ... Timothy EJ Behrens
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Neuroscience

    The self-interest of adolescents overrules cooperation in social dilemmas

    Xiaoyan Wu, Hongyu Fu ... Chao Liu
    Adolescents value reciprocity less than adults, limiting cooperation despite intact learning about others’ behavior.
    1. Neuroscience

    Psychedelic Drugs: Reshaping human neurons

    Jessica L Maltman, Javier González-Maeso
    Human neurons derived from stem cells show increased structural complexity and stronger synaptic connections after exposure to psilocin, the active metabolite of the psychedelic psilocybin.
    Version of Record
    Insight
    1. Neuroscience

    Functional specialization of mPFC–BLA and mPFC–NAc pathways in affective state representation

    Chien-Hsien Lai, Gyeongah Park ... Jianyang Du
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Neuroscience

    Pathogenic O-GlcNAc dyshomeostasis is associated with cortical malformations and hyperactivity

    Florence Authier, Asad Jan ... Daan MF van Aalten
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Cell Biology
    2. Neuroscience

    Death receptor 6 does not regulate axon degeneration and Schwann cell injury responses during Wallerian degeneration

    Bogdan Beirowski, Haoran Huang, Elisabetta Babetto
    Rigorous analysis in two knockout mouse lines demonstrates that death receptor 6 is not required for axon degeneration or Schwann cell injury responses following peripheral nerve transection.
    Version of Record
    Short Report
    • Valuable
    • Convincing
    1. Neuroscience

    Psilocin fosters neuroplasticity in iPSC-derived human cortical neurons

    Malin Schmidt, Anne Hoffrichter ... Philipp Koch
    Psilocin induces a durable neuroplastic state in human cortical neurons by enhancing BDNF signaling, neurite complexity, synaptogenesis, and synaptic network activity through 5-HT2A receptor-dependent mechanisms.
    1. Neuroscience

    Human exploration strategically balances approaching and avoiding uncertainty

    Yaniv Abir, Michael Neil Shadlen, Daphna Shohamy
    Strategic avoidance of uncertainty emerges under high cognitive demands, enabling faster decisions without impairing learning.
Load more

Highlights

    1. Neuroscience

    Psychedelic drugs and neuroplasticity

    Jessica L Maltman, Javier González-Maeso
    1. Neuroscience

    Stress, striatum and spirits

    1. Neuroscience

    Chronic neuropathic pain

    Geoffroy Laumet

Senior editors

  1. Timothy Behrens
    University of Oxford / University College London, United Kingdom
  2. Yanchao Bi
    Peking University, China
  3. Ma-Li Wong
    State University of New York Upstate Medical University, United States
  4. See more editors