Neuroscience

Neuroscience

eLife reviews research including brain function, neuronal circuits, synapses, sensory processing and motor pattern generation. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Neuroscience

    Longitudinal Central Adiposity Accumulation is Associated with Cortical Alteration and Impaired Cognitive Function in Adolescents

    Lingxuan Zhang, Bowen Qiu ... Dan Wu
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Neuroscience

    Dissociable roles of reward prediction error in the contrasting mood dynamics of depression and anxiety

    Zhihao Wang, Ting Wang ... Pengfei Xu
    Depression-specific symptoms blunt mood responses to unexpected outcomes, whereas anxiety-specific symptoms amplify them in non-clinical participants, with depression-related blunting also replicated in patients with affective disorders.
    1. Neuroscience

    PKD2L1 channels segregated to the apical compartment are the dual-mode pH sensor in cerebrospinal fluid-contacting neurons

    Magdalena Vitar, Daniel Prieto ... Federico F Trigo
    Apical PKD2L1 channels generate phasic and sustained currents that together make spinal cerebrospinal fluid-contacting neurons exquisite pH sensors.
    1. Neuroscience

    Reduced dorsal CA1 Activity Limits Retention of the Temporal Component of Declarative Memory in the Cntnap2 Knockout Mouse Model of Autism

    Elise C Rawlinson, Michael H McCullough ... Nathalie Dehorter
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Neuroscience

    Invariant synaptic density across species

    André Ferreira Castro, Albert Cardona
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Neuroscience

    When word order matters: human brains represent sentence meaning differently from large language models

    James Fodor, Carsten Murawski, Shinsuke Suzuki
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Solid
    1. Cell Biology
    2. Neuroscience

    Tau hyperphosphorylation impairs cooperative binding to microtubules and perturbs organelle trafficking in neurons

    Daniel Beaudet, Christopher L Berger, Adam G Hendricks
    Single-molecule motility assays and live-cell imaging in neurons reveal that tau hyperphosphorylation disrupts the formation of cooperative tau envelopes along microtubules and lysosomal transport.
    1. Neuroscience

    Selective lifelong suppression of an odor processing channel in response to critical period experience

    Hans C Leier, Julius Jonaitis ... Andrew M Dacks
    Utilizing the olfactory system of Drosophila, a critical period paradigm has provided new insight into the selectivity and longevity of the impact of early life experiences on sensory system circuitry.
    1. Medicine
    2. Neuroscience

    Reverse engineering of motor unit discharge in multiple sclerosis reveals heterogeneity of voluntary motor commands

    Laura M McPherson, Keith R Lohse ... Anne H Cross
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    • Incomplete
    1. Medicine
    2. Neuroscience

    Synthetic torpor in the rat protects the heart from ischaemia-reperfusion injury

    Megan Elley, Ludovico Taddei ... Michael Ambler
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
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Highlights

    1. Neuroscience
    Image credit: tama66 (CC0)

    How monkeys carve up the visual world

    Binxu Wang
    1. Neuroscience
    Image credit: geralt (CC0)

    Understanding the cellular architecture of Huntington’s disease

    Dorian Pustina
    1. Neuroscience
    Merrilee Schultz (CC0 via unsplash)

    Stronger memories through smarter stimulation

    Justin Riddle

Senior editors

  1. Joshua I Gold
    University of Pennsylvania, United States
  2. Tamar Makin
    University College London, United Kingdom
  3. Michael Taffe
    University of California, San Diego, United States
  4. See more editors