Figure 2—figure supplement 2. | TGF-β reduces DNA ds-break repair mechanisms to heighten genetic diversity and adaptability of CD44+/CD24− cancer cells

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TGF-β reduces DNA ds-break repair mechanisms to heighten genetic diversity and adaptability of CD44+/CD24− cancer cells

Figure 2—figure supplement 2.

Affiliation details

Cold Spring Harbor Laboratory, United States; Stony Brook University, United States; Huntington Hospital, Northwell Health, United States; University of Southern California, United States; Cancer Research UK – Cambridge Institute, University of Cambridge, United Kingdom
Figure 2—figure supplement 2.
Download figureOpen in new tabFigure 2—figure supplement 2. Differential mRNA expression of homology-directed repair (HDR) genes in multiple tumor-derived cell lines.

The chart represents mRNA expression analysis (SYBR-green-based RT-qPCR) of the indicated HDR genes that we observed to be downregulated in the H1650-M3 (CD44+/CD24−) cells across the indicated cell lines. The data represent mean ± SD of three replicates from two independent experiments.

DOI: http://dx.doi.org/10.7554/eLife.21615.012