321 results found
    1. Computational and Systems Biology
    2. Ecology

    Place recognition using batlike sonar

    Dieter Vanderelst, Jan Steckel ... Marc W Holderied
    Echolocating bats may recognize locations in the environment (and navigate to them) by remembering the specific echo signature of those locations.
    1. Ecology
    2. Physics of Living Systems

    Extreme suction attachment performance from specialised insects living in mountain streams (Diptera: Blephariceridae)

    Victor Kang, Robin T White ... Walter Federle
    Net-winged midge larvae use suction organs covered in spine-like cuticular protrusions to generate powerful attachment on wet and rough surfaces.
    1. Neuroscience

    Insulin sensitivity in mesolimbic pathways predicts and improves with weight loss in older dieters

    Lena J Tiedemann, Sebastian M Meyhöfer ... Stefanie Brassen
    Insulinergic neuromodulation of hedonic food processing predicts future weight management and improves with weight loss in older overweight dieters.
    1. Evolutionary Biology
    2. Structural Biology and Molecular Biophysics

    Prebiotic gas flow environment enables isothermal nucleic acid replication

    Philipp Schwintek, Emre Eren ... Dieter Braun
    Exponential nucleic acid replication can occur isothermally in a prebiotically plausible setting that accumulates and simultaneously separates the strands of nucleic acids through evaporation-driven flows at the gas–water interface.
    1. Cell Biology
    2. Chromosomes and Gene Expression

    Dedicated chaperones coordinate co-translational regulation of ribosomal protein production with ribosome assembly to preserve proteostasis

    Benjamin Pillet, Alfonso Méndez-Godoy ... Dieter Kressler
    A novel co-translational mechanism continuously adjusts the expression levels of ribosomal proteins Rpl3 and Rpl4 to their consumption during ribosome synthesis by regulating the abundance of their mRNAs.
    1. Neuroscience

    v-SNARE transmembrane domains function as catalysts for vesicle fusion

    Madhurima Dhara, Antonio Yarzagaray ... Dieter Bruns
    Structural flexibility of the synaptobrevin-2 transmembrane domain promotes membrane fusion.
    1. Computational and Systems Biology
    2. Structural Biology and Molecular Biophysics

    tRNA sequences can assemble into a replicator

    Alexandra Kühnlein, Simon A Lanzmich, Dieter Braun
    Rudimentary cross-catalytic replication can be established by double-hairpins of tRNA-like sequences, implying that replication and translation could have emerged along a common evolutionary trajectory.
    1. Neuroscience

    Key determinants of the dual clamp/activator function of Complexin

    Mazen Makke, Alejandro Pastor-Ruiz ... Dieter Bruns
    The amphipathic helix at the C-terminus of Complexin II prevents premature secretion, whereas its N-terminal domain regulates mechanisms which are governed by the forward rate of Ca2+ binding to Synaptotagmin I.
    1. Neuroscience

    A mechanism for exocytotic arrest by the Complexin C-terminus

    Mazen Makke, Maria Mantero Martinez ... Dieter Bruns
    The far C-terminal domain of CpxII interferes with SNARE assembly and thereby arrests tonic exocytosis.
    1. Neuroscience

    Synergistic actions of v-SNARE transmembrane domains and membrane-curvature modifying lipids in neurotransmitter release

    Madhurima Dhara, Maria Mantero Martinez ... Dieter Bruns
    Naturally-occurring v-SNARE TMD variants differentially regulate fusion pore dynamics and cooperate with phospholipids in supporting membrane curvature at the fusion pore neck.

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