8,998 results found
    1. Immunology and Inflammation

    Functionally diverse human T cells recognize non-microbial antigens presented by MR1

    Marco Lepore, Artem Kalinichenko ... Gennaro De Libero
    MR1T cells are human polyclonal T cells endowed with diverse effector functions in response to endogenous antigens presented by MHC-class 1-related molecule, MR1.
    1. Neuroscience

    Neural pattern change during encoding of a narrative predicts retrospective duration estimates

    Olga Lositsky, Janice Chen ... Kenneth A Norman
    Judgments of how much time elapsed between two events in a story are predicted by changes in fMRI activity patterns.
    1. Neuroscience

    Widespread correlation patterns of fMRI signal across visual cortex reflect eccentricity organization

    Michael J Arcaro, Christopher J Honey ... Uri Hasson
    Functional coupling between visual areas reflects supra-areal eccentricity organization distinct from overlapping receptive field connectivity during both rest conditions and naturalistic movie viewing.
    1. Genetics and Genomics

    miR-1 coordinately regulates lysosomal v-ATPase and biogenesis to impact proteotoxicity and muscle function during aging

    Isabelle Schiffer, Birgit Gerisch ... Adam Antebi
    Coordinate control of lysosomal v-ATPase subunits and biogenesis factor TFEB by miR-1 identifies a key regulatory axis with strong links to age-related proteotoxic disease.
    1. Neuroscience

    Mapping the human subcortical auditory system using histology, postmortem MRI and in vivo MRI at 7T

    Kevin R Sitek, Omer Faruk Gulban ... Federico De Martino
    MRI methods are promising techniques for investigating the human subcortical auditory system, and these publicly available data, atlases, and tools make researching human audition simpler and more reliable.
    1. Neuroscience

    Simultaneous brain, brainstem, and spinal cord pharmacological-fMRI reveals involvement of an endogenous opioid network in attentional analgesia

    Valeria Oliva, Ron Hartley-Davies ... Jonathan CW Brooks
    Attention-grabbing tasks produce rapid opioid-mediated analgesia via the descending pain modulation network to alter spinal neuronal activity.
    1. Neuroscience

    Non-invasive imaging of CSF-mediated brain clearance pathways via assessment of perivascular fluid movement with diffusion tensor MRI

    Ian F Harrison, Bernard Siow ... Jack A Wells
    The first non-invasive technique to assess the action of brain clearance mechanisms, driven by the perivascular inflow of cerebrospinal fluid, has been developed using magnetic resonance imaging.
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    1. Developmental Biology
    2. Physics of Living Systems

    Quantitative analyses reveal extracellular dynamics of Wnt ligands in Xenopus embryos

    Yusuke Mii, Kenichi Nakazato ... Shinji Takada
    Wnt distribution is regulated by a dynamic exchange of its abundant scaffold-bound and rare freely diffusing populations, providing insights into a conceived dilemma of speed and stability of tissue patterning.
    1. Neuroscience

    Neural underpinning of a respiration-associated resting-state fMRI network

    Wenyu Tu, Nanyin Zhang
    Using simultaneous recordings of electrophysiology, respiration, and resting-state fMRI, a respiration-associated neural network is identified.
    1. Developmental Biology

    LncEGFL7OS regulates human angiogenesis by interacting with MAX at the EGFL7/miR-126 locus

    Qinbo Zhou, Bo Yu ... Shusheng Wang
    lncEGFL7OS is a lncRNA located at the EGFL7/miR-126 locus that is critical for angiogenesis in humans.

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