SIT4 deletion and phosphate starvation increase mitochondrial membrane potential via electron transport chain dependent and independent manners, and the increased membrane potential induced by phosphate depletion is conserved between yeast, flies, and humans.

Phosphate starvation in rice induces widespread, but transient, modulation of DNA methylation near stress responsive genes that is independent from the RNA-directed DNA methylation pathway.

Analysis of inositol pyrophosphate dynamics upon inorganic phosphate (P_i) starvation identifies 1,5-IP₈ as the inositol pyrophosphate isomer signaling P_i sufficiency to the SPX domain of Pho81 that controls the transcriptional P_i starvation program.

The phosphate starvation response network in a commensal yeast evolved to expand its downstream targets via changes in the main transcription factor's dependence on its co-activator, potentially altering the physiological response.

The role of an amino acid-dependent tRNA modification as a nutrient sensor and regulator of metabolic homeostasis has been discovered.

Genetic and biochemical analysis of two enzymes reveals that inositol pyrophosphate signaling molecules allow plants to sense and regulate cellular phosphate levels, and to take up more phosphate when needed.

Real-time ³³P imaging combined with specific complementation of inorganic phosphate transport in the root cap reveals this tissue’s contribution to phosphate uptake.

A theoretical conceptualization of how phosphates control metabolic information flow and predictably regulate the metabolic state of the cell.

Cdk5-mediated stabilization of Acinus in postmitotic neurons promotes autophagy and the removal of protein aggregates linked to neurodegeneration in Drosophila melanogaster.

Nutrient starvation activates autophagy by a novel signaling mechanism that is blocked by one of the major autophagy inhibitors.