NFATc1 is identified as a molecular marker of articular cartilage progenitor cells and a transcriptional repressor of chondrocyte differentiation, providing fundamental insights into the origin and differentiation mechanism of articular chondrocytes.

Analyses of genetically engineered mouse models reveal the androgen receptor-independent properties of a luminal stem/progenitor cell in the prostate epithelium, and its ability to serve as a cell of origin for castration-resistant prostate cancer.

Neural progenitors in humans and chimpanzee organoids show remarkably similar cellular and molecular parameters, but metaphase is longer during human mitosis.

Paired analysis of gene expression and chromatin accessibility in SOX9+ lung progenitor cells identifies a requirement for PI3K in proximal-distal patterning of the mouse lung epithelium.

A single-cell transcriptomic study characterizes foxl2l-expressing germ cell progenitors important for female development in zebrafish and reveals the mechanism of sex differentiation.

Single-cell RNA sequencing of neonatal uterus revealed an Misr2+ endometrial stromal progenitor whose inhibition by ectopic administration of MIS caused uterine hypoplasia and infertility in adulthood.

Hematopoietic progenitor cells employ CD47 to engage thymic portal endothelial signal regulatory protein alpha for their transendothelial migration and thymic homing.

In patients with coronary artery disease, bone marrow myeloid progenitor cells are reprogrammed towards myeloid skewing and inflammatory activation.

Improved characterisation of human embryonic lung development highlights human-mouse differences and facilitates the development of defined culture conditions for the expansion of self-renewing, multipotent human lung epithelial progenitor cells.

SRSF10 directly binds genes functioning in spermatogonia and regulates their alternative splicing, the defect of which can lead to progenitor expansion failure.