74 results found
    1. Microbiology and Infectious Disease

    Streptomyces exploration is triggered by fungal interactions and volatile signals

    Stephanie E Jones, Louis Ho ... Marie A Elliot
    Exploratory growth is a newly discovered mode of Streptomyces growth that it is stimulated by fungi, is pH responsive, and can be communicated to other – physically separated – streptomycetes through airborne compounds.
    1. Microbiology and Infectious Disease

    Transcriptome dynamics of the Myxococcus xanthus multicellular developmental program

    José Muñoz-Dorado, Aurelio Moraleda-Muñoz ... Juana Pérez
    Investigation of global gene expression profiles during formation of the Myxococcus xanthus specialized biofilm reveals a genetic regulatory network that coordinates cell motility, differentiation, and secondary metabolite production.
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Pan-genome analysis identifies intersecting roles for Pseudomonas specialized metabolites in potato pathogen inhibition

    Alba Pacheco-Moreno, Francesca L Stefanato ... Andrew W Truman
    Genomics and genetics were used to identify specialized metabolites employed by Pseudomonas bacteria to suppress the growth of potato pathogens, which revealed a key role for cyclic lipopeptides.
    1. Microbiology and Infectious Disease

    Silencing cryptic specialized metabolism in Streptomyces by the nucleoid-associated protein Lsr2

    Emma J Gehrke, Xiafei Zhang ... Marie A Elliot
    In Streptomyces, the nucleoid-associated protein Lsr2 functions as a xenogenic silencer of foreign genes, and as a metabolic gatekeeper, repressing expression of both cryptic and well-studied specialized metabolic biosynthetic clusters.
    1. Ecology
    2. Microbiology and Infectious Disease

    Multiple lineages of Streptomyces produce antimicrobials within passalid beetle galleries across eastern North America

    Rita de Cassia Pessotti, Bridget L Hansen ... Matthew F Traxler
    The widespread occurrence of metabolically active streptomycetes in Odontotaenius disjunctus beetle frass may insulate their galleries against pathogenic fungal invasion through the production of diverse antimicrobial specialized metabolites.
    1. Neuroscience

    C. elegans avoids toxin-producing Streptomyces using a seven transmembrane domain chemosensory receptor

    Alan Tran, Angelina Tang ... Miri K VanHoven
    Caenorhabditis elegans require a GPCR to recognize and rapidly escape from toxin-producing Streptomyces at their head or tail.
    1. Ecology
    2. Microbiology and Infectious Disease

    Targeted induction of a silent fungal gene cluster encoding the bacteria-specific germination inhibitor fumigermin

    Maria Cristina Stroe, Tina Netzker ... Axel A Brakhage
    A silent gene cluster of the fungus Aspergillus fumigatus is activated by a bacterium and leads to the production of a novel spore germination inhibitor targeting the inducing bacterium.
    1. Microbiology and Infectious Disease

    Functional membrane microdomains and the hydroxamate siderophore transporter ATPase FhuC govern Isd-dependent heme acquisition in Staphylococcus aureus

    Lea Antje Adolf, Angelika Müller-Jochim ... Simon Heilbronner
    Staphylococcal heme acquisition needs a highly structured cell envelope, the membrane transporter accumulates in membrane domains most likely to allow concerted passage of heme from the cell wall-funnel to the membrane.
    1. Ecology
    2. Evolutionary Biology

    Nitric oxide radicals are emitted by wasp eggs to kill mold fungi

    Erhard Strohm, Gudrun Herzner ... Tobias Engl
    To protect their food and themselves against detrimental mould fungi, the eggs of a wasp species synthesize and emit remarkable amounts of gaseous nitrogen oxides that are highly effective antimicrobials.
    1. Microbiology and Infectious Disease

    Chromatin mapping identifies BasR, a key regulator of bacteria-triggered production of fungal secondary metabolites

    Juliane Fischer, Sebastian Y Müller ... Axel A Brakhage
    Genome-wide chromatin mapping during bacterial-fungal cocultivation identifies the Myb-like transcription factor BasR as the major regulatory node of bacteria-triggered production of fungal secondary metabolites.

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