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    1. Evolutionary Biology
    2. Genetics and Genomics

    Genealogy: The challenges of maintaining genetic privacy

    Shai Carmi
    Two studies suggest that a determined adversary may be able to obtain genetic information that they should not have permission to access from some genealogy databases.
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    1. Developmental Biology

    Cell Competition: Counting the Minutes

    Stephano Mello, Dirk Bohmann
    A newly discovered mechanism that causes the 'Minute' phenotype in fruit flies can explain how organisms are able to eliminate the mutant cells that arise occasionally during development.
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    1. Microbiology and Infectious Disease

    Viral Latency: Down but not out

    Erin T Larragoite, Adam M Spivak
    A new study in monkeys suggests that treating HIV infection early with antiretroviral therapy reduces the number of latent viruses, but has little impact on viral reactivation when treatment stops.
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  1. The silhouette of a head over a watercolour background

    Episode 62: December 2019

    In this episode we hear about bomb-proof tardigrades, how tuberculosis gets transmitted between cows and badgers, why ants do not get stuck in traffic jams, the state of mental health in academia and more.
    1. Evolutionary Biology

    Morphology: Too hip for two sacral vertebrae

    Michelle R Stocker
    A complex pelvic morphology has been discovered in the fossils of one of the largest crocodylians.
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    1. Cancer Biology

    Reproducibility in Cancer Biology: Rethinking research into metastasis

    Peter Friedl
    The partial success of an attempt to repeat findings in cancer biology highlights the need to improve study designs for preclinical research into metastasis and the targeting of cancer cells.
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    1. Computational and Systems Biology

    Meta-Research: Releasing a preprint is associated with more attention and citations for the peer-reviewed article

    Darwin Y Fu, Jacob J Hughey
    An analysis of more than 70,000 journal articles, including 5405 that were first released as a preprint on bioRxiv, shows that articles with a preprint received 49% more attention and 36% more citations than articles without one.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Cell Signaling: Uncovering the secret life of Rho GTPases

    Jenna A Perry, Amy Shaub Maddox
    New methods to directly visualize Rho GTPases reveal how a protein called RhoGDI regulates the activity of these 'molecular switches' at the plasma membrane.
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    1. Human Biology and Medicine
    2. Immunology and Inflammation

    Sepsis: Modelling survival

    Teresa A Zimmers, Leonidas G Koniaris
    A new mouse model of sepsis can reproduce the long-term muscle weakness seen in patients who survive this life-threatening illness.
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    1. Neuroscience

    Neurodegeneration: Fly model sheds light on brain disease

    Martin H Berryer et al.
    Experiments on flies suggest that a gain-of-function mechanism in a protein called CSPɑ contributes to the progressive brain disease CLN4.
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