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    1. Microbiology and Infectious Disease

    Tropical Diseases: Can CRISPR help in the fight against parasitic worms?

    Paul McVeigh, Aaron G Maule
    The first reports of CRISPR/Cas9 genome editing in flatworms could usher in a new era of research on these dangerous human parasites.
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  1. Episode 53: January 2019

    In this episode, we hear about memory consolidation, breast cancer, leafcutter ants, deep-sea biodiversity and the beneficial effects of oxytocin on our health.
    1. Human Biology and Medicine
    2. Microbiology and Infectious Disease

    Meta-Research: Gender inequalities among authors who contributed equally

    Nichole A Broderick, Arturo Casadevall
    An analysis of papers in which two or more authors shared first-author position found that male authors were more likely than female authors to appear first in the author list.
  2. The attendees of the Alliance4Life kick-off meeting

    Global Science: Forming an Alliance4Life

    Institutes from across central and eastern Europe are working together to improve the quality of research in the region.
    1. Cell Biology

    Autophagy: COPII vesicles and the expansion of the phagophore

    Catherine Rabouille
    A new study has identified the proteins that adapt COPII vesicles to the needs of starving cells.
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    1. Computational and Systems Biology

    Meta-Research: Incidences of problematic cell lines are lower in papers that use RRIDs to identify cell lines

    Zeljana Babic et al.
    The use of Research Resource Identifiers (RRIDs) improves the proper use of cell lines in the biomedical literature.
    1. Cell Biology
    2. Developmental Biology

    Mechanotransduction: How muscle contraction strengthens tendons

    Nicole O Glenn, Clarissa A Henry
    The force generated by muscles leads to signaling that helps to shape nearby tendon precursor cells.
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  3. Scientific Publishing: Progress and promise

    Randy Schekman
    As he prepares to step down as the Editor-in-Chief of eLife, Randy Schekman reflects on the origins of the journal, the eLife approach to peer review, and current challenges in scientific publishing.
    Editorial
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    1. Evolutionary Biology
    2. Structural Biology and Molecular Biophysics

    Protein Evolution: Building bigger beta-barrels

    Vikas Nanda
    The range of barrel-shaped proteins found in the outer membrane of certain bacteria evolved through multiple pathways.
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    1. Structural Biology and Molecular Biophysics

    Ion Channels: Solving a specificity mystery

    Sanduo Zheng, Andrew C Kruse
    Differences in the kinetics of G protein activation can explain why only some receptors can activate potassium ion channels called GIRKs.
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