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First Paper as PI: Kota Mizumoto
Tailoring your supervision style to fit individual students can be challenging, but watching their confidence grow and hearing about their ideas is rewarding.
Human Biology and Medicine
Point of View: Coordinating a new approach to basic research into Parkinson’s disease
Randy Schekman, Ekemini AU Riley
The ASAP initiative will incentivize collaboration between researchers and encourage open-science practices to improve our understanding of the biology underlying Parkinson's disease.
Intergenerational Effects: How maternal adversity impacts offspring
Zaneta M Thayer, Chlöe A Sweetman
Adversities experienced by female baboons early in life can affect the survival of their offspring years later.
Research Culture: A survey of new PIs in the UK
Sophie E Acton et al.
The challenges faced by new PIs in the UK include difficulties in recruiting PhD students, maintaining a good work-life balance and securing permanent positions.
Microbiology and Infectious Disease
Bacterial Protein Secretion: Looking inside an injection system
Sophie A Howard, Alain Filloux
The proteins injected by bacteria into eukaryotic organisms can lead to fates as diverse as death and metamorphosis.
Structural Biology and Molecular Biophysics
Transcription: Overcoming chromatin barriers
Babette E de Jong, John van Noort
Single-molecule experiments reveal the dynamics of transcription through a nucleosome with single-base-pair accuracy.
Speciation: How predictable is genome evolution?
Matthew J Coathup et al.
Similar patterns of genomic divergence have been observed in the evolution of plant species separated by oceans.
Biochemistry and Chemical Biology
Oxygen Sensors: When is a target not a target?
David C Bersten, Daniel J Peet
Cells rely on prolyl hydroxylase enzymes to sense low levels of oxygen, but they might act on fewer targets than previously thought.
Spatial Navigation: A question of scale
Muireann Irish, Siddharth Ramanan
An fMRI experiment reveals distinct brain regions that respond in a graded manner as humans process distance information across increasing spatial scales.
Physiology: The highs and lows of bird flight
Bar-headed geese lower their flight metabolic rates to fly in low-oxygen conditions.
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