Browse our Reviewed Preprints

1. 1. Biochemistry and Chemical Biology

   Identification of Suitable Target/E3 Ligase Pairs for PROTAC Development using a Rapamycin-induced Proximity Assay (RiPA)

   Bikash Adhikari, Katharina Schneider ... Elmar Wolf
2. 1. Microbiology and Infectious Disease

   Differences in HIV-1 reservoir size, landscape characteristics and decay dynamics in acute and chronic treated HIV-1 Clade C infection

   Kavidha Reddy, Guinevere Q Lee ... Thumbi Ndung’u
3. 1. Cancer Biology

   Unveiling chemotherapy-induced immune landscape remodeling and metabolic reprogramming in lung adenocarcinoma by scRNA-sequencing

   Yiwei Huang, Gujie Wu ... Cheng Zhan
4. 1. Stem Cells and Regenerative Medicine

   Nicotine enhances the stemness and tumorigenicity in intestinal stem cells via Hippo-YAP/TAZ and Notch signal pathway

   Ryosuke Isotani, Masaki Igarashi ... Toshimasa Yamauchi
5. 1. Immunology and Inflammation

   Distinct T Cell Receptor (TCR) gene segment usage and MHC-restriction between foetal and adult thymus

   Jasmine Rowell, Ching-In Lau ... Tessa Crompton
6. 1. Structural Biology and Molecular Biophysics

   Ab initio prediction of specific phospholipid complexes and membrane association of HIV-1 MPER antibodies by multi-scale simulations

   Colleen Maillie, Jay Golden ... Marco Mravic
7. 1. Ecology
   2. Computational and Systems Biology

   Microbes with higher metabolic independence are enriched in human gut microbiomes under stress

   Iva Veseli, Yiqun T Chen ... A Murat Eren
8. 1. Immunology and Inflammation
   2. Microbiology and Infectious Disease

   The Shigella flexneri effector IpaH1.4 facilitates RNF213 degradation and protects cytosolic bacteria against interferon-induced ubiquitylation

   Luz Saavedra-Sanchez, Mary S Dickinson ... Jörn Coers
9. 1. Microbiology and Infectious Disease

   Paracrine rescue of MYR1-deficient Toxoplasma gondii mutants reveals limitations of pooled in vivo CRISPR screens

   Francesca Torelli, Diogo M da Fonseca ... Moritz Treeck
10. 1. Medicine

    Estimating bone marrow adiposity from head MRI and identifying its genetic architecture

    Tobias Kaufmann, Pål Marius Bjørnstad ... Timothy Hughes