2,842 results found
    1. Neuroscience

    Release-dependent feedback inhibition by a presynaptically localized ligand-gated anion channel

    Seika Takayanagi-Kiya, Keming Zhou, Yishi Jin
    An anion-selective ligand gated channel acts as a presynaptic auto-receptor to modulate vesicle release and neuronal excitation.
    1. Neuroscience

    Context-dependent relationships between locus coeruleus firing patterns and coordinated neural activity in the anterior cingulate cortex

    Siddhartha Joshi, Joshua I Gold
    Simultaneous recordings in brainstem and cortex, combined with pupillometry, show that changes in coordinated activity in anterior cingulate cortex are related to distinct patterns of pupil-linked activation of the locus coeruleus-norepinephrine system.
    1. Neuroscience

    The cation channel mechanisms of subthreshold inward depolarizing currents in the mice VTA dopaminergic neurons and their roles in the chronic-stress-induced depression-like behavior

    Jing Wang, Min Su ... Hailin Zhang
    NALCN and TRPC6 drive the subthreshold depolarization of VTA DA neurons and down regulation of TRPC6 contributes to reduced VTA DA neuron firing and chronic stress-induced depression-like behavior of mice.
    1. Neuroscience

    ACC neural ensemble dynamics are structured by strategy prevalence

    Mikhail Proskurin, Maxim Manakov, Alla Karpova
    Anterior Cingulate Cortex displays robust tracking during strategy execution of a summary statistic for that strategy in recent behavioral history, suggesting a role for this brain region in estimating which actions promote the occurrence of events in the environment.
    1. Neuroscience

    Forniceal deep brain stimulation induces gene expression and splicing changes that promote neurogenesis and plasticity

    Amy E Pohodich, Hari Yalamanchili ... Huda Y Zoghbi
    Forniceal deep brain stimulation is a promising treatment for several neuropsychiatric disorders as it upregulates synaptic and neurogenesis-associated genes, normalizes genes misregulated in Rett syndrome mice, and regulates genes altered in intellectual disability and major depression.
    1. Neuroscience

    Interneuron-specific gamma synchronization indexes cue uncertainty and prediction errors in lateral prefrontal and anterior cingulate cortex

    Kianoush Banaie Boroujeni, Paul Tiesinga, Thilo Womelsdorf
    A fast spiking interneuron sub-type in medial and lateral prefrontal cortex fires and gamma-synchronizes prominently during adaptive learning of reward values when outcomes are uncertain and choice options have similar values.
    1. Microbiology and Infectious Disease
    2. Neuroscience

    Microbiota regulates visceral pain in the mouse

    Pauline Luczynski, Monica Tramullas ... John F Cryan
    Determining that microbiota-deficient mice have increased visceral pain, which can be reversed by restoring microbiota, may lead to novel microbial-based strategies for disorders associated with visceral pain.
    1. Chromosomes and Gene Expression

    Enhancer regions show high histone H3.3 turnover that changes during differentiation

    Aimee M Deaton, Mariluz Gómez-Rodríguez ... Robert E Kingston
    Nucleosomes at enhancers are unusually dynamic and change histone turnover rates during differentiation.
    1. Cell Biology
    2. Plant Biology

    Stretch-activated ion channels identified in the touch-sensitive structures of carnivorous Droseraceae plants

    Carl Procko, Swetha Murthy ... Joanne Chory
    Identification of putative mechanisms for mechanosensation-dependent prey capture in carnivorous plants.
    1. Chromosomes and Gene Expression
    2. Immunology and Inflammation

    Major transcriptional changes observed in the Fulani, an ethnic group less susceptible to malaria

    Jaclyn E Quin, Ioana Bujila ... Ann-Kristin Östlund Farrants
    Examining gene expression in the Fulani, an ethnic group relatively protected from malaria, identifies a more transcriptionally reactive response in cells of the innate immune system.

Refine your results by:

Type
Research categories