A novel mathematical strategy for the integrated analysis of adult body structures quantifies the degree and nature of developmental robustness and its evolutionary implications.

A single-cell atlas of the developing Drosophila wing disc at two time points enables a detailed understanding of the signals exchanged between different cell populations during development.

JNK signaling is active in developing Drosophila tissues and is required for achieving proper organ size.

A new approach measures the respective participations of elementary cell behaviors – such as cell division, intercalation, shape change and death – in the shaping of animal tissues.

Dpp emanating from the anterior-posterior compartment boundary is continuously required to promote proliferative growth of the whole fly wing appendage.

Radial patterns of cell morphology in the Drosophila larval wing emerge through mechanosensitive dynamics of cell polarity.

Proteolysis of lipidated N-terminal peptides that tether Hedgehog morphogens to the surface of source cells is absolutely required for their coupled release and bioactivation in vivo in Drosophila melanogaster.

Glypican proteins, required for morphogen signalling in Drosophila wing development, are endocytosed and degraded by the feedback regulator Pentagone.

Hedgehog acts as a morphogen by regulating proteolytic processing and activation of full-length Ci/Gli transcriptional effectors but can pattern Drosophila wing discs normally in the absence of regulated proteolytic processing.