447 results found
    1. Chromosomes and Gene Expression
    2. Developmental Biology

    N-terminus of Drosophila melanogaster MSL1 is critical for dosage compensation

    Valentin Babosha, Natalia Klimenko ... Oksana Maksimenko
    N‑terminus of MSL1 protein, involved in dosage compensation in Drosophila, is required for the interaction with non-coding roX2 RNA and the assembly of the complex on the male X chromosome.
    1. Plant Biology

    Cell-type-specific control of secondary cell wall formation by Musashi-type translational regulators in Arabidopsis

    Alicia Kairouani, Dominique Pontier ... Thierry Lagrange
    Musashi-mediated post-transcriptional mechanisms regulate glucuronoxylan modification and secondary cell wall formation in the supportive fibre cells of stem in plants.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    MOF-associated complexes ensure stem cell identity and Xist repression

    Tomasz Chelmicki, Friederike Dündar ... Asifa Akhtar
    Two complexes that contain the histone acetyl transferase MOF engage in a two-pronged approach to ensure the repression of X inactivation in mouse embryonic stem cells.
    1. Developmental Biology
    2. Neuroscience

    Transcriptional control of motor pool formation and motor circuit connectivity by the LIM-HD protein Isl2

    Yunjeong Lee, In Seo Yeo ... Mi-Ryoung Song
    Isl2 orchestrates specific hindlimb motor pool arrangement, guaranteeing accurate motor control and sensorimotor circuit functionality.
    1. Stem Cells and Regenerative Medicine
    2. Chromosomes and Gene Expression

    Mof-associated complexes have overlapping and unique roles in regulating pluripotency in embryonic stem cells and during differentiation

    Sarina Ravens, Marjorie Fournier ... Làszlò Tora
    Two complexes that contain the histone acetyl transferase MOF have distinct regulatory roles in the growth and development of pluripotent embryonic stem cells
    1. Genetics and Genomics

    Ssl2/TFIIH function in transcription start site scanning by RNA polymerase II in Saccharomyces cerevisiae

    Tingting Zhao, Irina O Vvedenskaya ... Craig D Kaplan
    Ssl2 processivity determines the window for transcription start site selection during promoter scanning by RNA polymerase II in Saccharomyces cerevisiae.
    1. Chromosomes and Gene Expression

    Msn2/4 regulate expression of glycolytic enzymes and control transition from quiescence to growth

    Zheng Kuang, Sudarshan Pinglay ... Jef D Boeke
    General stress response factors Msn2 and Msn4 activate glycolytic genes and promote acetyl-CoA accumulation to stimulate growth and proliferation of yeast cells under a nutrient-limiting condition, suggesting the unexpected interrelationship between carbohydrate metabolism and stress response.
    1. Genetics and Genomics

    Dynamics and regulatory roles of RNA m6A methylation in unbalanced genomes

    Shuai Zhang, Ruixue Wang ... Lin Sun
    Global analyses using aneuploid Drosophila revealed the dynamic roles of RNA m6A modification in regulating gene expression and development under genomic imbalance, highlighting its potential relationships with dosage-related effects.
    1. Chromosomes and Gene Expression

    Rapid epigenetic adaptation to uncontrolled heterochromatin spreading

    Jiyong Wang, Bharat D Reddy, Songtao Jia
    Redundant pathways prevent heterochromatin spreading and ectopic heterochromatin assembly; and plasticity of heterochromatin assembly allows cells to adapt to heterochromatin stress.
    1. Cell Biology
    2. Computational and Systems Biology

    Limits on information transduction through amplitude and frequency regulation of transcription factor activity

    Anders S Hansen, Erin K O'Shea
    The ability of cells to transmit information encoded in signaling dynamics is fundamentally limited by the gene decoding step.

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