Individuals with a history of adverse childhood experiences show blunted response to threat and reward irrespective of sample and paradigm characteristics and despite heterogeneity in adversity operationalization and assessment.
Hilda Björk Daníelsdóttir, Thor Aspelund ... Unnur Anna Valdimarsdóttir
Cumulative exposure to adverse childhood experiences is associated with lower adult resilience among women in a dose-dependent manner, independent of adult socioeconomic factors and social support, indicating that adult female resilience is consolidated in early life.
Maren Klingelhöfer-Jens, Katharina Hutterer ... Tina B Lonsdorf
Childhood adversity is associated with aberrant threat learning patterns in a large healthy adult sample as evidenced by empirically testing several theories linking childhood adversity to psychopathology.
As the United Kingdom braces for a sharp fall in living standards, a bioarchaeologist and a paediatrician discuss what the past can reveal about the social forces that shape modern health crises.
Huan Song, Henrik Larsson ... Unnur A Valdimarsdóttir
A population-based analysis demonstrates that surviving twins who lose their co-twins by death are at considerably elevated risks of developing psychiatric disorders.
Findings of this population-based sibling-matched cohort study corroborate an association of loss of a co-twin at birth with risk of psychiatric disorders, supporting the hypothesis of twin-bond development in utero.
Michael AP Bloomfield, Robert A McCutcheon ... Oliver Howes
Imaging and laboratory-induced psychosocial stress showed that exposure to psychosocial adversity was associated with dampened striatal dopaminergic function alongside blunted physiological yet potentiated subjective responses to acute stress.
In a randomized controlled trial in rural Bangladesh, an intensive, combined water, sanitation, handwashing, and nutrition intervention delivered to compounds of newborn children increased telomere length attrition during their first year of life.
Genetics, socioeconomic conditions, and family and school environments influence cognitive intelligence in children, and this impact may lead to the individual variability of the current and future PLEs.