43 results found
    1. Neuroscience

    How adverse childhood experiences get under the skin: A systematic review, integration and methodological discussion on threat and reward learning mechanisms

    Julia Ruge, Mana R Ehlers ... Tina B Lonsdorf
    Individuals with a history of adverse childhood experiences show blunted response to threat and reward irrespective of sample and paradigm characteristics and despite heterogeneity in adversity operationalization and assessment.
    1. Epidemiology and Global Health

    Adverse childhood experiences and resilience among adult women: A population-based study

    Hilda Björk Daníelsdóttir, Thor Aspelund ... Unnur Anna Valdimarsdóttir
    Cumulative exposure to adverse childhood experiences is associated with lower adult resilience among women in a dose-dependent manner, independent of adult socioeconomic factors and social support, indicating that adult female resilience is consolidated in early life.
    1. Neuroscience

    Reduced discrimination between signals of danger and safety but not overgeneralization is linked to exposure to childhood adversity in healthy adults

    Maren Klingelhöfer-Jens, Katharina Hutterer ... Tina B Lonsdorf
    Childhood adversity is associated with aberrant threat learning patterns in a large healthy adult sample as evidenced by empirically testing several theories linking childhood adversity to psychopathology.
  1. A hand gloved in blue holding a magenta spark on a grey background

    Health: Reading our future in the bones of children past

    As the United Kingdom braces for a sharp fall in living standards, a bioarchaeologist and a paediatrician discuss what the past can reveal about the social forces that shape modern health crises.
    1. Epidemiology and Global Health

    Risk of psychiatric disorders among the surviving twins after a co-twin loss

    Huan Song, Henrik Larsson ... Unnur A Valdimarsdóttir
    A population-based analysis demonstrates that surviving twins who lose their co-twins by death are at considerably elevated risks of developing psychiatric disorders.
    1. Epidemiology and Global Health

    Loss of a co-twin at birth and subsequent risk of psychiatric disorders

    Huan Song, Fang Fang ... Unnur A Valdimarsdóttir
    Findings of this population-based sibling-matched cohort study corroborate an association of loss of a co-twin at birth with risk of psychiatric disorders, supporting the hypothesis of twin-bond development in utero.
    1. Neuroscience

    The effects of psychosocial stress on dopaminergic function and the acute stress response

    Michael AP Bloomfield, Robert A McCutcheon ... Oliver Howes
    Imaging and laboratory-induced psychosocial stress showed that exposure to psychosocial adversity was associated with dampened striatal dopaminergic function alongside blunted physiological yet potentiated subjective responses to acute stress.
    1. Epidemiology and Global Health
    2. Medicine

    Effects of water, sanitation, handwashing, and nutritional interventions on telomere length among children in a cluster-randomized controlled trial in rural Bangladesh

    Audrie Lin, Benjamin F Arnold ... Stephen P Luby
    In a randomized controlled trial in rural Bangladesh, an intensive, combined water, sanitation, handwashing, and nutrition intervention delivered to compounds of newborn children increased telomere length attrition during their first year of life.
    1. Evolutionary Biology
    2. Genetics and Genomics

    High social status males experience accelerated epigenetic aging in wild baboons

    Jordan A Anderson, Rachel A Johnston ... Jenny Tung
    Among the factors that predict fitness in wild baboons, dominance rank in males, but not in females, is the best predictor of epigenetic aging.
    1. Medicine
    2. Neuroscience

    Gene–environment pathways to cognitive intelligence and psychotic-like experiences in children

    Junghoon Park, Eunji Lee ... Jiook Cha
    Genetics, socioeconomic conditions, and family and school environments influence cognitive intelligence in children, and this impact may lead to the individual variability of the current and future PLEs.

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