Christine R Collins, Fiona Hackett ... Michael J Blackman
Genetic analysis identifies an enzyme of the malaria parasite that is required to seal its host red blood cell membrane upon invasion, a key requirement of this important intracellular pathogen.
Comparative phylogenomic analyses based on a new reference-quality human Ascaris genome assembly reveals a pig/human interbred species complex with implications for Ascaris control worldwide.
Apicomplexan parasites secrete proteins to manipulate their hosts from sub-apical openings in their cell pellicle that are distinct from the apical complex from where invasion factors are secreted.
Well-controlled psychological experiments show that there is little overlap in how humans and convolutional networks classify adversarial images, highlighting the problem of using CNNs as models of human vision.
Echolocating toothed whales can detect and react to sudden prey movements during close approaches with speeds similar to ultra-fast tracking responses in human vision.
The crystal structures of the key vaccine candidate CyRPA alone and in complex with antibody Fab fragment was solved and this will be important information for designing a vaccine.
Plasmodium falciparum invasion protein EBA-175, once shed from the parasite surface post invasion, facilitates RBC clustering and enhances parasite growth while simultaneously enabling parasite immune evasion of host neutralizing antibodies.
New experiments and theory reveal how the ability to see image details depends upon photoreceptor function and eye movements, and how fruit flies (Drosophila) see spatial details beyond the optical limit of their compound eyes.
Deeptiman Chatterjee, Caique Almeida Machado Costa ... Wu-Min Deng
Comprehensive transcriptomic analyses describe the underlying tumorigenic gene expression state in the invasive Drosophila follicle cells following the loss of epithelial cell polarity and identify a non-canonical role of Keap1-Nrf2 signaling in regulating collective cell invasion.