Cell imaging and mathematical modelling show reciprocal cross-regulation between inflammatory signalling and cell cycle timing, which is mediated through functional interactions between NF-B and E2F proteins.

The molecular mechanisms beyond the bidirectionality (tTLP and tLTD) of endocanabinoid spike-timing dependent synaptic plasticity have been identified.

Extrasynaptic GABA_A receptors that emerge at puberty trigger adolescent synaptic pruning; pruning is prevented and cognition is impaired if the receptors are absent.

Rats act as if they expect that the delays associated with temporal cues will covary due to a common causal factor.

Visualized odor encounters show that Drosophila navigate spatiotemporally complex odor plumes using random walks biased by the timing of brief and unpredictable odor encounters.

Synaptotagmin-7 acts synergistically with synaptotagmin-1 by placing vesicles close to the plasma membrane within reach of the SNARE/Munc13-complex, supporting their priming and setting the stage for fast and slow fusion.

Polycomb enables lineage priming in mouse embryonic stem cells by establishing a barrier to commitment.

Genetic analyses revealed the critical role of local Wnt in neuronal patterning by instructing neurite pruning.

Neuronal activity in the striatum keeps track of elapsed time during the time production task while that in the cerebellum correlates with stochastic variation of self-timing in the range of several hundreds of milliseconds.

A minus-end-binding stabilizes minus-end-out microtubules in dendrites, which are required for dendrite-specific pruning during neuronal remodelling.