12,300 results found
    1. Neuroscience

    Resting-state fMRI signals contain spectral signatures of local hemodynamic response timing

    Sydney M Bailes, Daniel EP Gomez ... Laura D Lewis
    The frequency content of resting-state fMRI signals contains information that can characterize and predict local variations in hemodynamic response timing which enhances the temporal precision of fMRI.
    1. Physics of Living Systems

    Live imaging and biophysical modeling support a button-based mechanism of somatic homolog pairing in Drosophila

    Myron Barber Child VI, Jack R Bateman ... Hernan G Garcia
    Biophysical modeling and quantitative live-cell imaging converge to show that the century-old puzzle of somatic homolog pairing in Drosophila operates via a button model.
    1. Computational and Systems Biology
    2. Immunology and Inflammation

    Statistical inference reveals the role of length, GC content, and local sequence in V(D)J nucleotide trimming

    Magdalena L Russell, Noah Simon ... Frederick A Matsen IV
    Local sequence context, length, and GC nucleotide content in both directions of the trimming site, together, are highly predictive of V(D)J trimming probabilities for both TR and IG adaptive immune receptor loci.
    1. Computational and Systems Biology
    2. Genetics and Genomics

    Quantitative prediction of variant effects on alternative splicing in MAPT using endogenous pre-messenger RNA structure probing

    Jayashree Kumar, Lela Lackey ... Alain Laederach
    A novel model is presented that reconciles in-cell structure probing data with splicing regulatory elements to predict exon 10 inclusion of the Tau gene with high accuracy for 53 splice altering mutations.
    1. Biochemistry and Chemical Biology
    2. Epidemiology and Global Health

    Association of egg consumption, metabolic markers, and risk of cardiovascular diseases: A nested case-control study

    Lang Pan, Lu Chen ... Liming Li
    The associations of egg consumption with metabolic markers and of these markers with cardiovascular disease (CVD) risk showed opposite directions, which may partially explain the protective effect of moderate egg consumption on CVD in the Chinese population.
    1. Neuroscience

    Complementary cognitive roles for D2-MSNs and D1-MSNs during interval timing

    Robert A Bruce, Matthew Weber ... Kumar Narayanan
    Dorsomedial D2-MSNs and D1-MSNs exhibit opposing dynamics during interval timing, however disrupting either MSN type produces similar effects on behavior, highlighting the complementary roles of striatal pathways in cognitive operations.
    1. Chromosomes and Gene Expression

    Chromosome structure in Drosophila is determined by boundary pairing not loop extrusion

    Xinyang Bing, Wenfan Ke ... James B Jaynes
    Boundary:boundary pairing interactions drive TAD formation in Drosophila.
    1. Chromosomes and Gene Expression

    Stem-loop and circle-loop TADs generated by directional pairing of boundary elements have distinct physical and regulatory properties

    Wenfan Ke, Miki Fujioka ... James B Jaynes
    Boundary:boundary pairing generates either stem-loop or circle-loop TADs, and these loop topologies differ in how they impact chromosome structure and genetic activities.
    1. Neuroscience
    2. Physics of Living Systems

    Walking Drosophila navigate complex plumes using stochastic decisions biased by the timing of odor encounters

    Mahmut Demir, Nirag Kadakia ... Thierry Emonet
    Visualized odor encounters show that Drosophila navigate spatiotemporally complex odor plumes using random walks biased by the timing of brief and unpredictable odor encounters.
    1. Neuroscience

    Low-frequency neural activity reflects rule-based chunking during speech listening

    Peiqing Jin, Yuhan Lu, Nai Ding
    Neuroimaging reveals that the brain response to spoken language can be better explained by rule-based models than statistical models recently developed in artificial intelligence research.

Refine your results by:

Type
Research categories