Whole-genome in silico screening for stop codon contexts that produce elevated translational readthrough and peroxisome targeting reveals that in mammals, the amount of lactate dehydrogenase in the peroxisome is controlled by translational readthrough.

Ribosomes translate through stop codons far more often than previously thought, yielding C-terminally extended proteins in a variety of eukaryotes.

Ribosome profiling reveals genome-wide stimulation of stop codon readthrough by aminoglycosides that is influenced sequence context.

A majority of transcribed transposons during aging are derived from transcriptional defects, most notably intron retention and transcriptional readthrough.

The epitranscriptomic-driven mRNA polyadenylation pathway protects transcriptome integrity by restricting transcriptional read-throughs and RNA chimera formation in apicomplexan parasites and plants.

A new and efficient continuous flash suppression (CFS) method is presented that provides breakthrough and suppression thresholds to quantify depth of target suppression.

Disruption of the nucleosome DNA entry-exit site causes readthrough transcription of terminators, decreased nucleosome occupancy, and pervasive noncoding transcription, demonstrating this nucleosomal region protects the genome against inappropriate transcription.

Ribosomal profiling has shed new light on how ribosomes can ignore stop codons in messenger RNA.

Inhibition of bacterial protein synthesis by an antimicrobial peptide apidaecin triggers translation arrest at the stop codons, ribosome queuing and pervasive stop codon readthrough.