331 results found
    1. Developmental Biology
    2. Evolutionary Biology

    Dual mode of embryonic development is highlighted by expression and function of Nasonia pair-rule genes

    Miriam I Rosenberg, Ava E Brent ... Claude Desplan
    Pair-rule genes in the wasp Nasonia function as in Drosophila in patterning anterior segments, and similar to ancestral insects in patterning posterior segments, illustrating a mixed-mode transition state between short and long germ embryogenesis.
    1. Developmental Biology

    Geometric models for robust encoding of dynamical information into embryonic patterns

    Laurent Jutras-Dubé, Ezzat El-Sherif, Paul François
    Propagation, speed and shapes of genetic waves of expression during development can be modeled by a simple interplay between two transcriptional modules (dynamic/static), which explains robustness and precision of patterning.
    1. Developmental Biology

    The embryonic role of juvenile hormone in the firebrat, Thermobia domestica, reveals its function before its involvement in metamorphosis

    James W Truman, Lynn M Riddiford ... Michelle Herko
    This sesquiterpene hormone likely acted as a morphogenesis-to-differentiation switch in archaic embryos before it evolved its postembryonic function as the status quo regulator of insect metamorphosis.
    1. Developmental Biology
    2. Microbiology and Infectious Disease

    The Wolbachia cytoplasmic incompatibility enzyme CidB targets nuclear import and protamine-histone exchange factors

    John Frederick Beckmann, Gagan Deep Sharma ... Mark Hochstrasser
    Genetic and proteomic screening with Wolbachia's CidB enzyme reveal the mechanisms and targets of cytoplasmic incompatibility (CI).
    1. Computational and Systems Biology
    2. Developmental Biology

    A re-inducible gap gene cascade patterns the anterior–posterior axis of insects in a threshold-free fashion

    Alena Boos, Jutta Distler ... Ezzat El-Sherif
    The body axis of insects is divided into different fates using a self-regulatory and threshold-free mechanism.
    1. Developmental Biology
    2. Evolutionary Biology

    The mlpt/Ubr3/Svb module comprises an ancient developmental switch for embryonic patterning

    Suparna Ray, Miriam I Rosenberg ... François Payre
    mille-pattes micropeptides have conserved function in insect embryonic patterning together with transcription factor Shaven-baby and ubiquitin ligase Ubr3, except in flies wherein restoring broad embryonic Svb expression restores patterning potency.
    1. Evolutionary Biology

    The need for high-quality oocyte mitochondria at extreme ploidy dictates mammalian germline development

    Marco Colnaghi, Andrew Pomiankowski, Nick Lane
    Selective transfer of mitochondria in the Balbiani body ensures high-quality oocyte mitochondria at extreme ploidy, explaining many enigmatic features of female germline architecture including germ cell loss.
    1. Computational and Systems Biology
    2. Developmental Biology

    How enhancers regulate wavelike gene expression patterns

    Christine Mau, Heike Rudolf ... Ezzat El-Sherif
    An experimental and computational system has been developed to investigate how wavelike gene expression patterns are generated during embryonic development.
    1. Developmental Biology
    2. Evolutionary Biology

    A SoxB gene acts as an anterior gap gene and regulates posterior segment addition in a spider

    Christian Louis Bonatto Paese, Anna Schoenauer ... Alistair P McGregor
    Sox21b-1 regulates simultaneous formation of anterior segments and addition of posterior segments in a spider, which resembles segmentation in long- and short-germ insects, and suggests SoxB regulation of segmentation is an ancestral feature of arthropods.
    1. Evolutionary Biology

    Striking parallels between dorsoventral patterning in Drosophila and Gryllus reveal a complex evolutionary history behind a model gene regulatory network

    Matthias Pechmann, Nathan James Kenny ... Siegfried Roth
    Crucial functions of Toll signalling during dorsoventral axis formation might have evolved convergently in flies and crickets.

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