Models and experiments reveal that human L2/3 pyramidal neurons have distinctively low specific membrane capacitance which might have a significant impact on signal processing in human neocortex.

By acting as versatile signal-processors that encode flexible coordinate representations, muscle spindles challenge current widely held views concerning the role of proprioceptors and the peripheral nervous system in sensorimotor function.

The anterior insula cortex is a critical neural substrate of context-induced relapse of nicotine-seeking.

A novel methodical approach aimed at improving translation of network analyses to psychopathology provides an intuitive representation of longitudinal clinical pathways between symptoms and can assist in predicting prognosis.

The genome-organizer Satb2 has a key role in memory formation by modulating availability of miRNAs that control the function of synapses.

Larger dendritic diameter, increased conductance load at the soma, and differences in cable and ion channel properties enable faster signal propagation in human neocortical dendrites, preserving information processing speed.

Hedgehog acts as a morphogen by regulating proteolytic processing and activation of full-length Ci/Gli transcriptional effectors but can pattern Drosophila wing discs normally in the absence of regulated proteolytic processing.

The subcortical amygdala pathway, which has been traditionally associated with learning threats, is also required for processing an innate threat.

Curvature-preferring neurons in monkey V4 cluster into 0.5-mm patches, which highlights the importance of curvature detection in visual object recognition and the key functional role of V4 in this process.