In an investigation into the effects of drugs on proteins, an active machine learning algorithm chose which sets of experiments to perform and was able to learn an accurate model of the effects after doing only a fraction of the experiments.

Microtubule networks in frog egg extracts can spontaneously contract in a manner that can be quantitatively described by an active fluid model.

Sparse firing in a hippocampus-like structure of the teleost telencephalon is linked to spatial navigation and active sensing.

Global phosphoproteomic analysis in nerve terminal during exocytosis reveals 252 uniquely regulated phosphosites, highlighting complex regulation of active zone proteins at multiple sites and the role of specific kinases/phosphatases.

Maternally deposited Piwi-piRNA complexes co-transcriptionally repress transposable elements that transiently become active in somatic cells of the developing Drosophila embryo.

A cryo-electron microscopy model of the active human apoptosome illuminates how this "wheel of death" binds the protease procaspase-9 to initiate programmed cell death.

Clarinet, a novel C. elegans active zone protein with homology to vertebrate Piccolo and Rim, uses its different isoforms for diverse functions, including synaptic vesicle clustering, vesicle release and synaptogenesis.

RNA binding is a key input of an active chromatin complex and maintenance of stem cell fate.

Female, but not male rats exhibit an active conditioned fear response, which challenges traditional approaches to measuring fear learning exclusively through freezing, and suggests that females use a more diverse set of threat strategies.

High affinity interactions with transport adaptors are important to shield the interaction surfaces of cytomatrix components to block fatal premature oligomerization of active zone proteins during axonal transport.