701 results found
    1. Neuroscience

    The entorhinal-DG/CA3 pathway in the medial temporal lobe retains visual working memory of a simple surface feature

    Weizhen Xie, Marcus Cappiello ... Weiwei Zhang
    High-resolution fMRI data reveal an often-neglected contribution of the medial temporal lobe circuitry to item-specific representation in visual working memory, suggesting the mechanism traditionally deemed dedicated to long-term memory can be exploited to support the quality of human working memory.
    1. Neuroscience

    Cholinergic modulation of hippocampal calcium activity across the sleep-wake cycle

    Heng Zhou, Kevin R Neville ... Stephen N Gomperts
    Dynamic calcium activity in the hippocampus changes markedly across behavioral and physiological states and depends on muscarinic acetylcholine receptor activation.
    1. Neuroscience

    A dynamic neural resource model bridges sensory and working memory

    Ivan Tomić, Paul M Bays
    Psychophysical measurement and computational modeling show that sensory information cannot contribute directly to a cognitive judgment, but must first be integrated into resource-limited working memory.
    1. Neuroscience

    Inhibition in the auditory brainstem enhances signal representation and regulates gain in complex acoustic environments

    Christian Keine, Rudolf Rübsamen, Bernhard Englitz
    Inhibition in the brainstem has further roles beyond temporal sharpening and improves reproduction for a multitude of sounds.
    1. Neuroscience

    Activity in perirhinal and entorhinal cortex predicts perceived visual similarities among category exemplars with highest precision

    Kayla M Ferko, Anna Blumenthal ... Stefan Köhler
    The present findings reveal that subjectively perceived similarities between objects, including those unique to individual observers, are reflected with highest fidelity at the apex of the ventral visual pathway in the medial temporal lobe.
    1. Neuroscience

    Ionic mechanisms underlying history-dependence of conduction delay in an unmyelinated axon

    Yang Zhang, Dirk Bucher, Farzan Nadim
    Conduction velocity of action potentials in unmyelinated axons depends ultimately on the gating variables of the fast voltage-gated sodium current and can be predicted from the action potential peak and trough voltages.
    1. Neuroscience

    Real-time experimental control using network-based parallel processing

    Byounghoon Kim, Shobha Channabasappa Kenchappa ... Ari Rosenberg
    The Real-Time Experimental Control with Graphical User Interface (REC-GUI) framework can facilitate cutting-edge neuroscience research by providing precise experimental control using high-level programming environments familiar to many experimentalists.
    1. Developmental Biology

    Primed Track, high-fidelity lineage tracing in mouse pre-implantation embryos using primed conversion of photoconvertible proteins

    Maaike Welling, Manuel Alexander Mohr ... Periklis Pantazis
    Primed Track is an image analysis tool that allows for computational correction of drifting specimen to enable accurate lineage tracing of mammalian pre-implantation development even for larger imaging time intervals.
    1. Neuroscience

    The role of cochlear place coding in the perception of frequency modulation

    Kelly L Whiteford, Heather A Kreft, Andrew J Oxenham
    Human perceptual sensitivity to frequency modulation across the hearing range can be explained by a unitary neural code based on neural responses to amplitude modulation and fidelity of cochlear tuning.
    1. Neuroscience

    Evaluating hippocampal replay without a ground truth

    Masahiro Takigawa, Marta Huelin Gorriz ... Daniel Bendor
    A novel tool enables cross-checking the quality of replay events and evaluating the effectiveness of a given replay detection method in the absence of a ground truth.

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