Browse our latest Cancer Biology articles

Page 12 of 79
    1. Cancer Biology
    2. Cell Biology

    Distinct states of nucleolar stress induced by anticancer drugs

    Tamara A Potapova, Jay R Unruh ... Jennifer L Gerton
    Anticancer compound library screen identified many types of nucleolar stress and revealed an essential role of transcriptional cyclin-dependent kinases in nucleolar structure and function.
    1. Cancer Biology

    A positive feedback loop between ZEB2 and ACSL4 regulates lipid metabolism to promote breast cancer metastasis

    Jiamin Lin, Pingping Zhang ... Na Yang
    The ZEB2/ACSL4 axis acts as a novel metastatic metabolic pathway that stimulates both lipogenesis and fatty acid oxidation, resulting in enhanced breast cancer invasion and metastasis.
    1. Cancer Biology
    2. Computational and Systems Biology

    Pancreatic cancer symptom trajectories from Danish registry data and free text in electronic health records

    Jessica Xin Hjaltelin, Sif Ingibergsdóttir Novitski ... Søren Brunak
    A comprehensive comparison of the two types of pancreatic cancer symptom trajectories can in combination leverage a fuller potential of large health data and ultimately aid the detection of early risk factors for pancreatic cancer.
    1. Medicine
    2. Cancer Biology

    Development and Assessment of a Sustainable PhD Internship Program Supporting Diverse Biomedical Career Outcomes

    Patrick D. Brandt, Dawayne Whittington ... Rebekah L. Layton
    1. Cancer Biology
    2. Medicine

    Tissue-derived exosome proteomics identifies promising diagnostic biomarkers for esophageal cancer

    Dingyu Rao, Hua Lu ... Zhixian Tang
    Exosomal CD54 can be used as an effective biomarker for esophageal squamous cell carcinoma and CD54 promotes the proliferation and migration of tumor cells in vitro.
    1. Cancer Biology
    2. Cell Biology

    Treatment with tumor-treating fields (TTFields) suppresses intercellular tunneling nanotube formation in vitro and upregulates immuno-oncologic biomarkers in vivo in malignant mesothelioma

    Akshat Sarkari, Sophie Korenfeld ... Emil Lou
    Cancer-directed treatment using Tumor-Treating Fields spatially modulates the tumor microenvironment at the cellular and molecular levels, decreasing nanotube-based cellular networks of communication while creating a microenvironment more susceptible to immunotherapeutic strategies.
    1. Cancer Biology

    Molecular portraits of colorectal cancer morphological regions

    Eva Budinská, Martina Hrivňáková ... Vlad Popovici
    Tumor morphological patterns are linked to distinct transcriptional profiles and may indicate the need for a multi-site tumor sampling in gene expression-based studies.
    1. Cancer Biology
    2. Medicine

    Discovery and biological evaluation of a potent small molecule CRM1 inhibitor for its selective ablation of extranodal NK/T cell lymphoma

    He Liu, Meisuo Liu ... Yongliang Yang
    Deep reinforcement model and experimental evaluations identified a small-molecule CRM1 inhibitor that can selectively ablate extranodal NK/T cell lymphoma cells.
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