Browse our latest Cancer Biology articles

Identifying the regulators of a non-genetic mechanism (ERCYS) that is constitutively activated in cancer cells to provide pro-survival properties.

Single-cell imaging and mass spectrometry data reveal adenosine in the DNA of mammalian cells can be methylated by METTL3 to form N6-methyladenosine in response to DNA damage.

Oncogene permanent activation in a single targeted cell of zebrafish together with a reprogramming factor transient activation is sufficient to induce the malignant transformation of the cell and tumor development.

Genome-wide CRISPR screen identified propionyl-CoA subunit B as a key regulator for anti-tumor T-cell activity in pancreatic cancer, which holds promise for advancing immunotherapy strategies in curing pancreatic cancer.

NAP-CNB, a machine learning platform, accurately identifies tumor neoantigens, where higher tumor expression correlates with optimal antitumor activity, and multiantigen vaccination enhances immune responses.

Derived from scRNA-seq, SLC26A3 is a potential therapeutic target to improve the efficacy of immunotherapy, as well as a potential diagnostic indicator to reduce post-surgical upstaging, for cervical adenocarcinoma.

Plectin drives hepatocellular carcinoma progression and metastasis through cytoskeletal reorganization and oncogenic signaling, making it a promising therapeutic target for overcoming therapy resistance.

The stem cell signal Msi2 plays a dual role in lung cancer, acting as a signal that is not only essential for initiation, but also for propagation of the tumor.