Browse our latest Cancer Biology articles

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    1. Cancer Biology

    Targeting the Hippo pathway in cancers via ubiquitination dependent TEAD degradation

    Trang H. Pham, Kanika Bajaj Pahuja ... Anwesha Dey
    1. Cancer Biology
    2. Genetics and Genomics

    Single-cell sequencing highlights heterogeneity and malignant progression in actinic keratosis and cutaneous squamous cell carcinoma

    Dan-Dan Zou, Ya-Zhou Sun ... Xin Li
    A single-cell RNA profiling analysis has delineated the molecular changes driving the progression from actinic keratosis to cutaneous squamous cell carcinoma.
    1. Cancer Biology

    Disseminating cells in human oral tumours possess an EMT cancer stem cell marker profile that is predictive of metastasis in image-based machine learning

    Gehad Youssef, Luke Gammon ... Adrian Biddle
    Cancer stem cells that have undergone EMT are identified in the region surrounding metastatic human oral tumours in a retrospective cohort study, and these are predictive of metastatic outcome in an image-based machine learning approach.
    1. Cancer Biology

    Single-cell characterization of human GBM reveals regional differences in tumor-infiltrating leukocyte activation

    Philip Schmassmann, Julien Roux ... Gregor Hutter
    A regionally resolved single-cell RNA-sequencing analysis of GBM-associated leukocytes reveals distinct activation states of the main immune populations between tumor center, peripheral infiltration zone and blood.
    1. Cancer Biology
    2. Epidemiology and Global Health

    Identifying metabolic features of colorectal cancer liability using Mendelian randomization

    Caroline Bull, Emma Hazelwood ... Emma E Vincent
    Increased genetic liability to colorectal cancer is associated with altered levels of circulating metabolites, including fatty acids, up to 40 years before average age of diagnosis.