Browse our latest Cancer Biology articles

Biochemical, transcriptomic, and proteomic analyses reveal that protein arginine methyltransferases post-transcriptionally regulate intron detention—introns that persist in nuclear polyadenylated RNA—through methylation of RNA splicing and processing factors.

Genome sequencing analysis dissects the origins and evolution of cancer transmission between clam species in the Seas of Southern Europe.

G alpha q/11 signaling can either promote or inhibit melanocyte growth through a reversible switch that is controlled by the microenvironment and that shapes the mutational diversity of melanoma subtypes.

A novel quantitative framework to analyse the inner structure of tumour spheroids in terms of the mechanisms that underly growth.

Pancreatic cancers can utilize hyaluronic acid, an abundant extracellular matrix component in the tumor microenvironment, to fuel cancer cell metabolism and growth.

A novel multi-hormones secreting chromaffin-like cell type was identified using single-cell RNA sequencing, suggesting the molecular mechanism of ectopic ACTH and CRH pheochromocytoma associated with Cushing’s syndrome.

Heat shock factor 1 is involved in estrogen-induced chromatin remodeling in estrogen receptor-positive breast cancer cells.

A vasoactive molecular imaging probe provides capability for sensitive functional imaging of cancer-associated protease activity in vivo.

NMNAT is genetically required for glioma development and promotes glioma growth by allowing a higher tolerance to DNA damage and inhibiting DNA damage-p53-caspase-3 apoptosis signaling pathway by enhancing NAD⁺-dependent posttranslational modifications (PTMs) poly(ADP-ribosyl)ation (PARylation) and deacetylation of p53.

ZHX2 controls HIF1α oncogenic signaling and tumorigenesis in triple-negative breast cancer.