Browse our latest Cell Biology articles

ORMDL3 promotes RIG-I degradation to suppress type I interferon signaling pathway and antiviral immune response, highlighting ORMDL3 as a potential therapeutic target in viral infection and cancer immunotherapy.

ATP6V0A1 was identified as a key player in nephropathic cystinosis-related renal pathology, with antioxidants like ATX emerging as potential treatments to restore V0A1 expression, mitochondrial function, and balance autophagic processes.

The rete ovarii is a complex secretory structure that may play an important role in ovarian homeostasis.

Long thought to have little relevance to ovarian physiology, the rete ovarii may have a role in follicular dynamics and reproductive health.

Imaging and correlative light and electron microscopy analyses of endosomal-lysosomal organellar assembly in mammalian oocytes elucidated statistic alteration in their size, distribution, and correlation with endo-lysosomal maturation during oocyte-to-embryo transition.

A differentiable variant of the Gillespie algorithm enables gradient-based optimization for stochastic chemical kinetics, facilitating efficient parameter estimation and the design of biochemical networks with desired input–output relationships.