Browse our latest Cell Biology articles

Page 13 of 317
    1. Cell Biology
    2. Evolutionary Biology

    Evolutionary rescue of spherical mreB deletion mutants of the rod-shape bacterium Pseudomonas fluorescens SBW25

    Paul Richard J Yulo, Nicolas Desprat ... Heather L Hendrickson
    Fitness defects arising from deletion of the gene encoding the bacterial equivalent of actin (mreB) are readily compensated by mutations affecting cell wall synthesis.
    1. Cell Biology

    CDK-mediated phosphorylation of PNKP is required for end-processing of single-strand DNA gaps on Okazaki fragments and genome stability

    Kaima Tsukada, Rikiya Imamura ... Mikio Shimada
    It was revealed that phosphorylation of the DNA repair enzyme PNKP at threonine 118 by CDK is required for DNA replication through the gap filling of Okazaki fragments.
    1. Cell Biology

    Oxidized low-density lipoprotein potentiates angiotensin II-induced Gq activation through the AT1-LOX1 receptor complex

    Jittoku Ihara, Yibin Huang ... Koichi Yamamoto
    Oxidized LDL synergizes with angiotensin II to amplify Gq signaling via the AT1-LOX1 receptor complex, revealing a novel mechanism driving renal dysfunction in hypertension and dyslipidemia.
    1. Cell Biology
    2. Neuroscience

    Aβ-driven nuclear pore complex dysfunction alters activation of necroptosis proteins in a mouse model of Alzheimer’s disease

    Vibhavari Aysha Bansal, Jia Min Tan ... Toh Hean Ch'ng
    Characterization of nuclear pore loss and dysfunction in nucleocytoplasmic compartmentalization in Alzheimer's disease neurons.
    1. Cell Biology
    2. Evolutionary Biology

    Identification and comparison of orthologous cell types from primate embryoid bodies shows limits of marker gene transferability

    Jessica Jocher, Philipp Janssen ... Ines Hellmann
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Cell Biology

    ORMDL3 restrains type I interferon signaling and anti-tumor immunity by promoting RIG-I degradation

    Qi Zeng, Chen Yao ... Shuai Chen
    ORMDL3 promotes RIG-I degradation to suppress type I interferon signaling pathway and antiviral immune response, highlighting ORMDL3 as a potential therapeutic target in viral infection and cancer immunotherapy.
    1. Cell Biology

    Novel mechanism for tubular injury in nephropathic cystinosis

    Swastika Sur, Maggie Kerwin ... Minnie M Sarwal
    ATP6V0A1 was identified as a key player in nephropathic cystinosis-related renal pathology, with antioxidants like ATX emerging as potential treatments to restore V0A1 expression, mitochondrial function, and balance autophagic processes.
    1. Cell Biology
    2. Developmental Biology

    Rediscovering the rete ovarii, a secreting auxiliary structure to the ovary

    Dilara N Anbarci, Jennifer McKey ... Blanche Capel
    The rete ovarii is a complex secretory structure that may play an important role in ovarian homeostasis.
    1. Cell Biology
    2. Developmental Biology

    Ovarian Biology: Revisiting the rete ovarii

    Yan Zhang, Hua Zhang
    Long thought to have little relevance to ovarian physiology, the rete ovarii may have a role in follicular dynamics and reproductive health.
    Version of Record
    Insight