Browse our latest Cell Biology articles

Page 12 of 320
    1. Cell Biology

    Force transmission through the inner kinetochore is enhanced by centromeric DNA sequences

    Elise Miedlar, Grace E Hamilton ... Trisha N Davis
    Biochemical reconstitution and laser trapping show that centromeric DNA sequences are important for the transmission of microtubule-based forces to chromosomes.
    1. Cell Biology

    Optogenetic control of a GEF of RhoA uncovers a signaling switch from retraction to protrusion

    Jean de Seze, Maud Bongaerts ... Mathieu Coppey
    A single protein can switch cellular behaviors from protrusion to retraction based on its concentration and dynamics, revealing a novel mechanism for controlling antagonistic phenotypes in cell signaling.
    Version of Record
    Research Article
    • Important
    • Compelling
    • Convincing
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Scrutinized lipid utilization disrupts Amphotericin-B responsiveness in clinical isolates of Leishmania donovani

    Supratim Pradhan, Dhruba Dhar ... Budhaditya Mukherjee
    Nutritional adaptations in Leishmania donovani enable persistent antimony resistance and reduced Amphotericin-B effectiveness by selectively exploiting host lipids and limiting cholesterol mobilization.
    1. Cell Biology
    2. Cancer Biology

    GMCL1 Controls 53BP1 Stability and Modulates Paclitaxel Sensitivity in Cancer

    Yuki Kito, Tania J González-Robles ... Michele Pagano
    Not revised
    Reviewed Preprint v1
    • Inadequate
    1. Cell Biology

    Extracellular vesicle-mediated release of bis(monoacylglycerol)phosphate is regulated by LRRK2 and Glucocerebrosidase activity

    Elsa Meneses-Salas, Marianna Arnold ... Albert Lu
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    • Inadequate
    1. Cell Biology

    Periosteal skeletal stem cells can migrate into the bone marrow and support hematopoiesis after injury

    Tony Marchand, Kemi E Akinnola ... Kira Gritsman
    A femur transplantation model of bone marrow regeneration highlights the plasticity of periosteal skeletal stem cells and their ability to contribute to bone marrow niche regeneration, ultimately facilitating hematopoietic regeneration.
    1. Cell Biology
    2. Neuroscience

    Vision: A pathway to sight

    Katherine J Wert
    The breakdown of glutamine is an important metabolic pathway for the health and survival of rod photoreceptors within the retina.
    Version of Record
    Insight
    1. Cell Biology
    2. Neuroscience

    Glutamine catabolism supports amino acid biosynthesis and suppresses the integrated stress response to promote photoreceptor survival

    Moloy T Goswami, Eric Weh ... Thomas J Wubben
    For the first time, mouse models reveal the metabolic dependency of photoreceptors on glutamine catabolism in vivo and further demonstrate the flexibility of photoreceptors to utilize fuel sources beyond glucose.
    1. Cell Biology
    2. Medicine

    Endometriosis is not the endometrium: Reviewing the over-representation of eutopic endometrium in endometriosis research

    Kate Gunther, Teagan Fisher ... Caroline Elizabeth Ford
    Nearly half of sequencing data labeled as endometriosis lacks true disease representation, highlighting the urgent need for more diverse and accurate tissue sampling to advance research in this underrepresented field.
    1. Cell Biology
    2. Microbiology and Infectious Disease

    A novel SUN1-ALLAN complex coordinates segregation of the bipartite MTOC across the nuclear envelope during rapid closed mitosis in Plasmodium berghei

    Mohammad Zeeshan, Igor Blatov ... Rita Tewari
    The SUN1-ALLAN complex serves as a nuclear envelope–spanning tether that coordinates the segregation of a bipartite microtubule organising center (MTOC) during the unusual mitosis of Plasmodium.