Elise Miedlar, Grace E Hamilton ... Trisha N Davis
Biochemical reconstitution and laser trapping show that centromeric DNA sequences are important for the transmission of microtubule-based forces to chromosomes.
A single protein can switch cellular behaviors from protrusion to retraction based on its concentration and dynamics, revealing a novel mechanism for controlling antagonistic phenotypes in cell signaling.
A femur transplantation model of bone marrow regeneration highlights the plasticity of periosteal skeletal stem cells and their ability to contribute to bone marrow niche regeneration, ultimately facilitating hematopoietic regeneration.
For the first time, mouse models reveal the metabolic dependency of photoreceptors on glutamine catabolism in vivo and further demonstrate the flexibility of photoreceptors to utilize fuel sources beyond glucose.
Kate Gunther, Teagan Fisher ... Caroline Elizabeth Ford
Nearly half of sequencing data labeled as endometriosis lacks true disease representation, highlighting the urgent need for more diverse and accurate tissue sampling to advance research in this underrepresented field.
The SUN1-ALLAN complex serves as a nuclear envelope–spanning tether that coordinates the segregation of a bipartite microtubule organising center (MTOC) during the unusual mitosis of Plasmodium.