Browse our latest Cell Biology articles

Page 14 of 322
    1. Cell Biology

    Sphingolipid imbalance aggravates tau pathology by endomembrane rigidification and rupture

    Jessica Tittelmeier, Carl Alexander Sandhof ... Carmen Nussbaum-Krammer
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    • Incomplete
    1. Cell Biology

    JAK-STAT pathway activation compromises nephrocyte function in a Drosophila high-fat diet model of chronic kidney disease

    Yunpo Zhao, Jianli Duan ... Zhe Han
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    • Solid
    1. Cell Biology

    ACVR2A facilitates trophoblast cell invasion through TCF7/c-JUN pathway in pre-eclampsia progression

    Shujing Yang, Huanyao Liu ... Fang He
    ACVR2A downregulation disrupts the TCF7/c-JUN pathway, impairing trophoblast invasion and proliferation in pre-eclampsia, revealing a genetic susceptibility-associated mechanism of placental dysfunction.
    1. Cell Biology
    2. Developmental Biology

    Mutations that prevent phosphorylation of the BMP4 prodomain impair proteolytic maturation of homodimers leading to lethality in mice

    Hyung-Seok Kim, Mary L Sanchez ... Jan L Christian
    Phosphorylation of the BMP4 prodomain is required for proteolytic activation of BMP4 homodimers, but not BMP4/7 heterodimers.
    1. Cell Biology

    Force transmission through the inner kinetochore is enhanced by centromeric DNA sequences

    Elise Miedlar, Grace E Hamilton ... Trisha N Davis
    Biochemical reconstitution and laser trapping show that centromeric DNA sequences are important for the transmission of microtubule-based forces to chromosomes.
    1. Cell Biology

    Optogenetic control of a GEF of RhoA uncovers a signaling switch from retraction to protrusion

    Jean de Seze, Maud Bongaerts ... Mathieu Coppey
    A single protein can switch cellular behaviors from protrusion to retraction based on its concentration and dynamics, revealing a novel mechanism for controlling antagonistic phenotypes in cell signaling.
    Version of Record
    Research Article
    • Important
    • Compelling
    • Convincing
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Scrutinized lipid utilization disrupts Amphotericin-B responsiveness in clinical isolates of Leishmania donovani

    Supratim Pradhan, Dhruba Dhar ... Budhaditya Mukherjee
    Nutritional adaptations in Leishmania donovani enable persistent antimony resistance and reduced Amphotericin-B effectiveness by selectively exploiting host lipids and limiting cholesterol mobilization.
    1. Cell Biology
    2. Cancer Biology

    GMCL1 Controls 53BP1 Stability and Modulates Paclitaxel Sensitivity in Cancer

    Yuki Kito, Tania J González-Robles ... Michele Pagano
    Not revised
    Reviewed Preprint v1
    • Inadequate
    1. Cell Biology

    Extracellular vesicle-mediated release of bis(monoacylglycerol)phosphate is regulated by LRRK2 and Glucocerebrosidase activity

    Elsa Meneses-Salas, Marianna Arnold ... Albert Lu
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    • Inadequate
    1. Cell Biology

    Periosteal skeletal stem cells can migrate into the bone marrow and support hematopoiesis after injury

    Tony Marchand, Kemi E Akinnola ... Kira Gritsman
    A femur transplantation model of bone marrow regeneration highlights the plasticity of periosteal skeletal stem cells and their ability to contribute to bone marrow niche regeneration, ultimately facilitating hematopoietic regeneration.
Newer articles Older articles