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Page 14 of 324
    1. Cancer Biology
    2. Cell Biology

    Phosphodiesterase 1A physically interacts with YTHDF2 and reinforces the progression of non-small cell lung cancer

    Chong Zhang, Zuoyan Zhang ... Yangling Li
    Uncovering a novel PDE1A/YTHDF2/STAT3 pathway in non-small cell lung cancer (NSCLC) progression also provides therapeutic strategies for treating NSCLC patients with metastasis.
    1. Cell Biology

    Targeting the WSB2–NOXA axis in cancer cells for enhanced sensitivity to BCL-2 family protein inhibitors

    Dongyue Jiao, Kun Chang ... Chenji Wang
    Disrupting WSB2-mediated NOXA degradation sensitizes cancer cells to apoptosis and provides a new strategy to overcome resistance to BCL-2 inhibition.
    1. Cell Biology

    Lymphatic System: Closing in on pacemaker cells

    Pin-Ji Lei, Timothy P Padera
    Lymphatic muscle cells orchestrate the contraction of collecting lymphatic vessels in mice.
    Version of Record
    Insight
    1. Cell Biology

    ATG2A engages RAB1A and ARFGAP1 positive membranes during autophagosome biogenesis

    Devin M Fuller, Yumei Wu ... Thomas J Melia
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Cancer Biology
    2. Cell Biology

    A single cysteine residue in vimentin regulates long non-coding RNA XIST to suppress epithelial–mesenchymal transition and stemness in breast cancer

    Saima Usman, William Andrew Yeudall ... Ahmad Waseem
    Disruption of vimentin–actin interaction induces XIST expression and drives epithelial-to-mesenchymal transition and stem cell-like traits in breast cancer cells, enhancing oncogenic behaviour in nude mice independent of oestrogen.
    1. Cell Biology
    2. Immunology and Inflammation

    G1 and G2 ApolipoproteinL1 modulate macrophage inflammation and lipid accumulation through the polyamine pathway

    Esther Liu, Matthew Wright ... Jennie Lin
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Decoding protein phosphorylation during oocyte meiotic divisions using phosphoproteomics

    Leonid Peshkin, Enrico maria Daldello ... Catherine Jessus
    A comprehensive resource describes protein abundance and phosphorylation dynamics during Xenopus oocyte maturation, serving as an essential tool for investigating the molecular mechanisms driving meiotic progression.
    1. Cell Biology
    2. Physics of Living Systems

    Convergent Cellular Adaptation to Freeze-Thaw Stress via a Quiescence-like State in Yeast

    Charuhansini Tvishamayi, Farhan Ali ... Shashi Thutupalli
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Cell Biology
    2. Neuroscience

    The myeloid cell-driven transdifferentiation of endothelial cells into pericytes promotes the restoration of BBB function and brain self-repair after stroke

    Tingbo Li, Ling Yang ... Jie-Min Jia
    Changes in the pericyte pool after stroke affect the restoration of the blood-brain barrier function and brain self-repair, and offer a new approach to therapy.
    1. Cell Biology
    2. Developmental Biology

    Inducible, virus-free direct lineage reprogramming enhances scalable generation of human inner ear hair cell-like cells

    Robert N Rainey, Sam D Houman ... Neil Segil
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
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