Browse our latest Cell Biology articles

Page 177 of 327
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    The speed of GTP hydrolysis determines GTP cap size and controls microtubule stability

    Johanna Roostalu, Claire Thomas ... Thomas Surrey
    GTPase-deficient microtubules are hyper-stable and have longer EB binding regions, demonstrating that EBs bind the GTP cap.
    1. Cell Biology
    2. Structural Biology and Molecular Biophysics

    The kinesin-5 tail domain directly modulates the mechanochemical cycle of the motor domain for anti-parallel microtubule sliding

    Tatyana Bodrug, Elizabeth M Wilson-Kubalek ... Jawdat Al-Bassam
    Biochemical, single molecule, cell and structural biology studies reveal an interaction between the kinesin-5 tail and motor domains regulating high-force production, which is critical for microtubule sliding motility.
    1. Cell Biology
    2. Neuroscience

    The orphan receptor GPR88 blunts the signaling of opioid receptors and multiple striatal GPCRs

    Thibaut Laboute, Jorge Gandía ... Jérôme AJ Becker
    GPR88 inhibits G-protein signaling of nearby GPCRs, and dampens b-arrestin recruitment by all GPCRs tested, likely by sequestration in intracellular compartments.
    1. Cell Biology
    2. Plant Biology

    Evolutionarily unique mechanistic framework of clathrin-mediated endocytosis in plants

    Madhumitha Narasimhan, Alexander Johnson ... Jiří Friml
    The examination of the ultra-structure and in vivo dynamics of endocytosis in plants reveal plants unique actin-independent, clathrin-mediated endocytosis mechanisms to overcome their unique physiological properties.
    1. Cell Biology
    2. Developmental Biology

    Notochord vacuoles absorb compressive bone growth during zebrafish spine formation

    Jennifer Bagwell, James Norman ... Michel Bagnat
    Live imaging and genetic analyses revealed that notochord vacuoles play a critical role in spine morphogenesis by absorbing vertebral bone growth, thus implicating notochord mechanics in congenital scoliosis.
    1. Cell Biology

    Kinesin Kif2C in regulation of DNA double strand break dynamics and repair

    Songli Zhu, Mohammadjavad Paydar ... Aimin Peng
    Kinesin Kif2C is recruited to DNA damage sites, modulates the mobility and dynamics of DNA damage foci, and promotes DNA double strand break repair.
    1. Cell Biology
    2. Plant Biology

    Microscopy: Looking below the surface in plants

    Rui Wang, Anna A Dobritsa
    A new way to culture and image flowers is uncovering the processes that take place in reproductive cells buried deep in plants.
    Version of Record
    Insight
    1. Cell Biology
    2. Plant Biology

    Imaging plant germline differentiation within Arabidopsis flowers by light sheet microscopy

    Sona Valuchova, Pavlina Mikulkova ... Karel Riha
    Light sheet microscopy was used to establish a method for live imaging of cellular events within Arabidopsis flower and for constructing a 3D model of flower at subcellular resolution.
    1. Cell Biology
    2. Neuroscience

    Small-molecule G-quadruplex stabilizers reveal a novel pathway of autophagy regulation in neurons

    Jose F Moruno-Manchon, Pauline Lejault ... Andrey S Tsvetkov
    G-quadruplex DNA regulates autophagy in neurons.
    1. Cell Biology
    2. Developmental Biology

    Recruitment of mRNAs to P granules by condensation with intrinsically-disordered proteins

    Chih-Yung S Lee, Andrea Putnam ... Geraldine Seydoux
    The intrinsically-disordered protein MEG-3 recruits mRNAs to P granules by forming gel-like condensates with ribosome-depleted mRNAs.