Browse our latest Cell Biology articles

Disease-associated mutations in BICD2 result in loss- and gain-of-function interactions and dynein hyperactivity.

In vitro reconstitution identifies how lysosome-related vacuoles coordinate the synthesis and turnover of inorganic polyphosphates to create a powerful buffer system stabilising a vital metabolic parameter, the cytosolic concentration of phosphate.

Restitution of RAP2A, human homolog of Drosophila asymmetric cell division regulator Rap2l, in glioblastoma neurosphere cultures targets the stemness of glioblastoma stem cells and could contribute to reduce glioblastoma expansion.

RAB27A-dependent mitochondrial recruitment of SYTL5 promotes mitophagy and mitochondrial bioenergetics upon hypoxia.

Distinct SMC5/6 subcomplexes mediate the transcriptional silencing of circular extrachromosomal DNA (SIMC1–SLF2) and repair of chromosomal DNA lesions (SLF1–SLF2), thus enabling exploration of SMC5/6 functions in innate immunity and cancer.

The metabolic fate of a nutrient called pyruvate determines how big cells become.

Chromosome-driven DnaA activity oscillations, modulated by DNA-binding proteins, enable bacteria to coordinate DNA replication with biomass growth independently of transcriptional regulation.