Browse our latest Cell Biology articles

Page 22 of 330
    1. Cell Biology
    2. Developmental Biology

    The full-length BEND2 protein is dispensable for spermatogenesis but required for setting the ovarian reserve in mice

    Yan Huang, Nina Bucevic ... Ignasi Roig
    Disrupting full-length BEND2 impairs ovarian reserve establishment without causing male sterility, highlighting a sex-specific role in fertility and offering new insights into genetic contributions to infertility diagnosis and reproductive health.
    1. Cell Biology
    2. Neuroscience

    The promise and peril of comparing fluorescence lifetime in biology revealed by simulations

    Pingchuan Ma, Peter Chen ... Yao Chen
    A versatile computational framework realistically simulates fluorescence lifetime data in biological systems, enhancing rigor by quantifying signal variance and identifying limitations, and enabling innovations such as multiplexed dynamic biosensor imaging.
    1. Cell Biology
    2. Developmental Biology

    Transcriptional dynamics uncover the role of BNIP3 in mitophagy during muscle remodeling in Drosophila

    Hiroki Taoka, Tadayoshi Murakawa ... Naonobu Fujita
    A time-course RNA-seq analysis of muscle remodeling reveals transcriptional dynamics independent of autophagy and highlights the significance of BNIP3 in mitochondrial degradation in vivo.
    1. Cancer Biology
    2. Cell Biology

    PRMT1-mediated metabolic reprogramming promotes leukemogenesis

    Hairui Su, Yong Sun ... Xinyang Zhao
    Glycolysis and attenuates oxidative phosphorylation through long-chain fatty acids, while mitochondrial biogenesis and anabolism remain intact, to accelerate the progression of acute megakaryocytic leukemia.
    1. Cell Biology

    Membrane Biology: Nothing can replace polyunsaturated lipids

    Sofia Rodriguez-Gallardo, Takeshi Harayama
    Genetic studies reveal that polyunsaturated lipids do more than simply increase the fluidity of the cell membrane.
    Version of Record
    Insight
    1. Cell Biology

    Hexokinase regulates Mondo-mediated longevity via the PPP and organellar dynamics

    Raymond Laboy, Marjana Ndoci ... Adam Antebi
    Hexokinases regulate the metabolic transcription factor MML-1 via distinct pathways, linking glucose metabolism and organellar signaling to longevity control in Caenorhabditis elegans and mammals.
    1. Cell Biology

    N-cadherin mechanosensing in ovarian follicles controls oocyte maturation and ovulation

    Alaknanda Emery, Orest W Blaschuk ... Darryl L Russell
    A critical role for N-cadherin in ovarian follicular development and ovulation is demonstrated with inhibitors or knockout of N-cadherin shown to inhibit ovulation by blocking mechanotransduction of ovulatory genes.
    1. Cell Biology
    2. Neuroscience

    Development of the axonal βII-spectrin periodic skeleton requires active cytoskeletal remodelling

    Shivani Bodas, Ashish Mishra ... Aurnab Ghose
    Not revised
    Reviewed Preprint v1
    • Useful
    • Convincing
    1. Structural Biology and Molecular Biophysics
    2. Cell Biology

    A biochemical mechanism for Stu2/XMAP215-family microtubule polymerases

    Binnu Gangadharan, Daniel L Kober, Luke M Rice
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Cancer Biology
    2. Cell Biology

    Phosphodiesterase 1A physically interacts with YTHDF2 and reinforces the progression of non-small cell lung cancer

    Chong Zhang, Zuoyan Zhang ... Yangling Li
    Uncovering a novel PDE1A/YTHDF2/STAT3 pathway in non-small cell lung cancer (NSCLC) progression also provides therapeutic strategies for treating NSCLC patients with metastasis.