Browse our latest Cell Biology articles

Page 271 of 318
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    ABHD17 proteins are novel protein depalmitoylases that regulate N-Ras palmitate turnover and subcellular localization

    David Tse Shen Lin, Elizabeth Conibear
    Palmitate turnover is controlled by distinct enzyme families with different specificities.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Protein translocation channel of mitochondrial inner membrane and matrix-exposed import motor communicate via two-domain coupling protein

    Rupa Banerjee, Christina Gladkova ... Dejana Mokranjac
    Two domains of the peripheral membrane protein Tim44 interact with two different sectors of a translocase to coordinate the translocation of proteins across the inner mitochondrial membrane.
    1. Structural Biology and Molecular Biophysics
    2. Cell Biology

    A K+-selective CNG channel orchestrates Ca2+ signalling in zebrafish sperm

    Sylvia Fechner, Luis Alvarez ... U Benjamin Kaupp
    Zebrafish sperm display an unusual pathway for Ca2+ signalling.
    1. Cell Biology
    2. Chromosomes and Gene Expression

    Fcp1 phosphatase controls Greatwall kinase to promote PP2A-B55 activation and mitotic progression

    Rosa Della Monica, Roberta Visconti ... Domenico Grieco
    The phosphatase Fcp1 inactivates Greatwall kinase at the end of mitosis.
    1. Cell Biology
    2. Computational and Systems Biology

    An analysis toolbox to explore mesenchymal migration heterogeneity reveals adaptive switching between distinct modes

    Hamdah Shafqat-Abbasi, Jacob M Kowalewski ... Staffan Strömblad
    “Discontinuous” and “Continuous” migration modes are divergent mesenchymal migration strategies that arise spontaneously in parallel in an equilibrium modulated by cell-matrix attachment and actomyosin contractility.
    1. Cell Biology
    2. Neuroscience

    Dendritic mitochondria reach stable positions during circuit development

    Michelle C Faits, Chunmeng Zhang ... Daniel Kerschensteiner
    Mitochondria reach stable positions in dendrites during a critical developmental period of high motility.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Kindlin-2 cooperates with talin to activate integrins and induces cell spreading by directly binding paxillin

    Marina Theodosiou, Moritz Widmaier ... Reinhard Fässler
    Kindlin-2 co-operates with talin to activate fibronectin-binding integrins on fibroblasts and subsequently induces cell spreading by recruiting paxillin to small, peripheral nascent adhesions.
    1. Cell Biology

    Intracellular sphingosine releases calcium from lysosomes

    Doris Höglinger, Per Haberkant ... Carsten Schultz
    Sphingosine acts as a lipid messenger molecule in intracellular signaling networks that are relevant to lysosomal function and Niemann-Pick disease.
    1. Cell Biology

    A gene-expression screen identifies a non-toxic sumoylation inhibitor that mimics SUMO-less human LRH-1 in liver

    Miyuki Suzawa, Diego A Miranda ... Holly A Ingraham
    The FDA-approved compound and plant extract tannic acid is a non-toxic chemical tool for modulating sumoylation in multiple platforms.
    1. Cell Biology
    2. Developmental Biology

    The tumor suppressor PTEN and the PDK1 kinase regulate formation of the columnar neural epithelium

    Joaquim Grego-Bessa, Joshua Bloomekatz ... Kathryn V Anderson
    In addition to its role in regulating proliferation and cell death, the PTEN tumor suppressor regulates epithelial morphogenesis through the PDK1 kinase.