Anthony J Covarrubias, Halil Ibrahim Aksoylar ... Tiffany Horng
Interleukin 4 signaling co-opts the Akt-mTORC1-Acly pathway to couple metabolic input to the control of energetically demanding processes during macrophage M2 activation.
Anna P Baron, Conrad von Schubert ... Erich A Nigg
Chemical inhibition of Bub1 shows that the catalytic activity is not required for normal mitotic progression, but it makes chromosome segregation and cell proliferation more sensitive to the effects of the anti-cancer drug Paclitaxel.
Martin Steger, Francesca Tonelli ... Matthias Mann
Discovery of a physiological LRRK2 substrate and a new mechanism of Rab regulation should aid Parkinson’s research and the understanding of Rab function.
Zachary B Katz, Brian P English ... Robert H Singer
A method that involves simultaneous tracking of individual mRNAs and their associated ribosomes can be used to determine when and where individual molecules get translated in living cells.