Browse our latest Cell Biology articles

Page 275 of 333
    1. Cell Biology
    2. Developmental Biology

    Pentagone internalises glypicans to fine-tune multiple signalling pathways

    Mark Norman, Robin Vuilleumier ... George Pyrowolakis
    Glypican proteins, required for morphogen signalling in Drosophila wing development, are endocytosed and degraded by the feedback regulator Pentagone.
    1. Physics of Living Systems
    2. Cell Biology

    Dynamic curvature regulation accounts for the symmetric and asymmetric beats of Chlamydomonas flagella

    Pablo Sartori, Veikko F Geyer ... Jonathon Howard
    The self-organised beat of cilia and flagella is dynamically regulated by curvature.
    1. Structural Biology and Molecular Biophysics
    2. Cell Biology

    Atypical calcium regulation of the PKD2-L1 polycystin ion channel

    Paul G DeCaen, Xiaowen Liu ... David E Clapham
    Outward calcium ion currents desensitize the human PKD2-L1 ion channel via a mechanism that is independent of cytosolic motifs.
    1. Cell Biology

    Exercise promotes the expression of brain derived neurotrophic factor (BDNF) through the action of the ketone body β-hydroxybutyrate

    Sama F Sleiman, Jeffrey Henry ... Moses V Chao
    A potential link between metabolic changes resulting from exercise and gene expression in the brain has been revealed.
    1. Cell Biology
    2. Neuroscience

    The endoplasmic reticulum, not the pH gradient, drives calcium refilling of lysosomes

    Abigail G Garrity, Wuyang Wang ... Haoxing Xu
    The endoplasmic reticulum serves as a direct and primary source of calcium ions for the lysosome.
    1. Cancer Biology
    2. Cell Biology

    ERG signaling in prostate cancer is driven through PRMT5-dependent methylation of the Androgen Receptor

    Zineb Mounir, Joshua M Korn ... Raymond A Pagliarini
    The transcription factor ERG recruits the PRMT5 enzyme to methylate the androgen receptor, presenting a post-translational regulatory mechanism that could be therapeutically exploited to control cell proliferation.
    1. Cell Biology
    2. Chromosomes and Gene Expression

    Opposing roles of nuclear receptor HNF4α isoforms in colitis and colitis-associated colon cancer

    Karthikeyani Chellappa, Poonamjot Deol ... Frances M Sladek
    Proper gut health depends on the balance between two naturally occurring variants of a transcription factor in the colon.
    1. Cell Biology
    2. Stem Cells and Regenerative Medicine

    A feedback amplification loop between stem cells and their progeny promotes tissue regeneration and tumorigenesis

    Jun Chen, Na Xu ... Rongwen Xi
    A newly discovered feedback amplification loop between stem cells and their immediate daughter progenitor cells drives epithelial regeneration and tumor development.
    1. Cell Biology
    2. Immunology and Inflammation

    Notch1 regulated autophagy controls survival and suppressor activity of activated murine T-regulatory cells

    Nimi Marcel, Apurva Sarin
    Notch1 activates autophagy to regulate the survival of T-regulatory cells from mice.
    1. Cell Biology

    Selective sorting and destruction of mitochondrial membrane proteins in aged yeast

    Adam L Hughes, Casey E Hughes ... Daniel E Gottschling
    A new mitochondrial protein degradation pathway selectively sorts and destroys a subset of the mitochondrial membrane proteome to protect mitochondria in times of stress.