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Caprin-2 is up-regulated in the rat hypothalamus by osmotic stress and controls vital homeostatic osmoregulatory mechanisms by altering the length of the poly(A) tail on arginine vasopressin mRNAs.

The aging lineage of budding yeast is differentiated by an early-appearing protein deposit that promotes protein quality control.

Building on previous work (Conduit et al., 2014), and contrary to what was previously thought, it is shown that key centrosomal proteins are not recruited to centrosomes as part of large multi-protein assemblies.

Deletion of one gene can lead to inactivation of other genes which restore a perturbed cellular function but change the epistatic interactions and the dynamics of the responsible module.

An interaction between the ion channel ASIC1a and the protein RIP1 is responsible for neuronal death caused by tissue acidosis.

NMR spectroscopy has been used to explain a central unresolved issue of nuclear transport, namely how it can be both fast and specific.

SPOP mutations underlie a novel, genomically unstable subclass of prostate cancer by altering DNA repair.

A protein kinase complex that is important for cell division is lost in testicular seminoma, which is a common cancer in men.

Contractility wins over the polarity pathway in a tug-of-war to position a cytokinesis-like actomyosin ring at the equator of notochord cells.