Browse our latest Cell Biology articles

Page 277 of 317
    1. Structural Biology and Molecular Biophysics
    2. Cell Biology

    The molecular mechanism of nuclear transport revealed by atomic-scale measurements

    Loren E Hough, Kaushik Dutta ... David Cowburn
    NMR spectroscopy has been used to explain a central unresolved issue of nuclear transport, namely how it can be both fast and specific.
    1. Cell Biology
    2. Cancer Biology

    SPOP mutation leads to genomic instability in prostate cancer

    Gunther Boysen, Christopher E Barbieri ... Mark A Rubin
    SPOP mutations underlie a novel, genomically unstable subclass of prostate cancer by altering DNA repair.
    1. Cell Biology
    2. Cancer Biology

    Prostate Cancer: SPOP the mutation

    Leah Rider, Scott D Cramer
    Version of Record
    Insight
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    A mitotic kinase scaffold depleted in testicular seminomas impacts spindle orientation in germ line stem cells

    Heidi Hehnly, David Canton ... John D Scott
    A protein kinase complex that is important for cell division is lost in testicular seminoma, which is a common cancer in men.
    1. Structural Biology and Molecular Biophysics
    2. Cell Biology

    Assembly and positioning of actomyosin rings by contractility and planar cell polarity

    Ivonne M Sehring, Pierre Recho ... Di Jiang
    Contractility wins over the polarity pathway in a tug-of-war to position a cytokinesis-like actomyosin ring at the equator of notochord cells.
    1. Cell Biology
    2. Developmental Biology

    Matrix metalloproteinase 14 is required for fibrous tissue expansion

    Susan H Taylor, Ching-Yan Chloé Yeung ... Karl E Kadler
    The membrane type I-matrix metalloproteinase is essential for the release of collagen fibrils from plasma membrane fibripositors, which is required for the transition from embryonic to postnatal tendon development.
    1. Cell Biology

    Paradoxical resistance of multiple myeloma to proteasome inhibitors by decreased levels of 19S proteasomal subunits

    Diego Acosta-Alvear, Min Y Cho ... Martin Kampmann
    The nodes of the cytosolic proteostasis network can control sensitivity to proteasome inhibitors and decreased levels of the 19S proteasomal regulator can lead to increased resistance to inhibitors.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Physiological modulation of BiP activity by trans-protomer engagement of the interdomain linker

    Steffen Preissler, Joseph E Chambers ... David Ron
    Interdomain linker-mediated oligomerization of the endoplasmic reticulum chaperone protein BiP responds to the unfolded protein burden
    1. Cell Biology
    2. Developmental Biology

    NOCA-1 functions with γ-tubulin and in parallel to Patronin to assemble non-centrosomal microtubule arrays in C. elegans

    Shaohe Wang, Di Wu ... Karen Oegema
    The C. elegans ninein homolog NOCA-1 is important for the assembly of non-centrosomal microtubule arrays required for embryo production, nuclear positioning and larval development.
    1. Cell Biology
    2. Developmental Biology

    In vivo dynamics of skeletal muscle Dystrophin in zebrafish embryos revealed by improved FRAP analysis

    Fernanda Bajanca, Vinicio Gonzalez-Perez ... Simon M Hughes
    A multidisciplinary approach was used to translate the mathematical analysis of Dystrophin movements inside muscle cells into the biology of how Dystrophin interacts with the cell membrane.